The Asian Chemical Editorial Society (ACES) is an organization of 13 major chemical societies in Asia and the Pacific. It was founded in 2005 as a conglomeration of chemical societies with the mutual aim of creating a modern publishing forum for research in Asia and coordinating future publishing activities.
The participating societies share a commitment to scientific excellence, to publishing ethics, and to the highest standards in publication, which are the basis for the success of Chemistry—An Asian Journal and its associated journals.
A sister journal of Angewandte Chemie and Chemistry—A European Journal
A sister journal of the European Journal of Organic Chemistry
For the publication of the AsianJOC, ACES is joined by the Korean Society of Organic Synthesis.
Supporting Organization: ChemPubSoc Europe
ACES supports the publication of the ChemPubSoc Europe journals Chemistry—A European Journal, the European Journal of Organic Chemistry, and ChemSusChem.
© Wiley-VCH 2012
A Good Year
Chem. Asian J. 2014 9, 4.
There's an App for That
Asian J. Org. Chem. 2014 3, 3.
To be or not to be (cationic)? In the presence of monomer, neutral 16-electron N-heterocyclic carbene adducts of high oxidation state MoVI N-arylimidoalkylidene bis(triflate) complexes convert into cationic 16-electron complexes that are active and functional-group tolerant polymerization catalysts.
Michael R. Buchmeiser, Suman Sen, Jörg Unold, Wolfgang Frey
Angew. Chem. Int. Ed. 2014, 53, No. 35, 9384. Read article.
Stuck on Au: A model system is defined that allows the quantification of nanoparticle adsorption energy under conditions that satisfy the assumptions of the Langmuir adsorption model. This advance could enable fundamental studies of nanoparticles relating to adsorption chemistry, biological processes, and materials by design.
Matthew N. O'Brien, Boya Radha, Keith A. Brown, Matthew R. Jones, Chad A. Mirkin
Angew. Chem. Int. Ed. 2014, 53, No. 36, 9532. Read article.
Coming up for air: Cu/nitroxyl catalysts for aerobic alcohol oxidation have been developed that exhibit near-ideal reaction conditions: operation at room temperature, use of ambient air as the oxidant, and complete reaction within one hour. These methods, together with related amine oxidations, have the potential to be the first class of aerobic oxidation reactions widely used in organic chemistry.
Bradford L. Ryland, Shannon S. Stahl
Angew. Chem. Int. Ed. 2014, 53, No. 34, 8824. Read article.
This Focus Review describes recent efforts in developing light-controlled switchable compounds and their applications in biological systems. In particular, photoisomerization reactions of azobenzene as well as synthetic green fluorescent protein chromophores are discussed.
Asian J. Org. Chem. 2014, 3, No. 8, 830. Read article.
A strong aversion to water: In an approach to water-resistant porous materials with a superhydrophobic surface without the use of alkylation or fluorination, a porous coordination polymer was synthesized with a low-symmetry nanoscale organic linker. The material exhibited superhydrophobicity (see picture) as a result of the surface corrugation created by the aromatic hydrocarbon and displayed selective uptake of organic molecules from water.
Koya Prabhakara Rao, Masakazu Higuchi, Kenji Sumida, Shuhei Furukawa, Jingui Duan, Susumu Kitagawa
Angew. Chem. Int. Ed. 2014, 53, No. 31, 8225. Read article.
A diketopyrrolopyrrole (DPP) dimer is synthesized by combining electron-rich benzodithiophene-thiophene and electron-deficient DPP. It has energy levels what match with [6,6]-phenyl-C71-butyric acid methyl ester (PC71BM) and a broad UV/vis absorption spectrum. With PC71BM as the acceptor, the power conversion efficiency is 3.90 %, the short-circuit current density is 9.85 mA cm−2, the open-circuit voltage is 0.71 V, and the fill factor is 0.57.
Zhixiao Niu, Xue Wang, Jianhua Huang, Ailing Tang, Yuxi Sun, Chuanlang Zhan
Asian J. Org. Chem. 2014, 3, No. 9, 948. Read article.
The structure–function relationship of a U-turn motif in the terminal loop of a synthetic neomycin riboswitch has been investigated. The analysis revealed those nucleobases required to optimize riboswitch function at every single position. A detailed comparison of functional and inactive mutants revealed a relationship between aptamer dynamics and regulation efficiency.
Julia E. Weigand, Sina R. Gottstein-Schmidtke, Shemsi Demolli, Florian Groher, Elke Duchardt-Ferner, Jens Wöhnert, Beatrix Suess
ChemBioChem 2014, 15, No. 11, 1627. Read article.
We have developed aza-[4+3] annulation via successive [3+2]-[2+1] cycloaddition-aza-Cope rearrangement for the synthesis of dihydroazepines. Aza-[3+2] annulation was accomplished via [3+2]-[2+1]-aza-Cope rearrangement-1,3-migration or [3+2]-[2+1]-Clock rearrangement to give dihydropyrroles along with molecular nitrogen. This procedure was applied to a one-pot process starting from terminal alkynes, azides, and dienes.
Sanghyuck Kim, Juntae Mo, Jaeeun Kim, Taekyu Ryu, Phil Ho Lee
Asian J. Org. Chem. 2014, 3, No. 9, 926. Read article.
A bit bulkier is too much: A combined experimental and computational DFT study has shown that the terminal to bridging transformation of an amidinate–tetrylene unit on a dicobalt carbonyl complex is negligibly influenced by the nature of the tetrylene Group 14 donor atom (Si or Ge; see figure), but is strongly dependent upon the steric hindrance exerted by the amidinate N-R groups because the reaction is thermodynamically favorable for R=iPr but not for R=tBu.
Javier A. Cabeza, Pablo García-Alvarez, Enrique Pérez-Carreño, Diego Polo
Chem. Eur. J. 2014, 20, No. 28, 8654. Read article.
O, I say! An N-formylmorpholine (NFM)-modulated one-pot glycosylation was used for the synthesis for construction of 1,2-cis α-glycosidic linkages in the synthesis of the pentasaccharide repeating unit of the O-antigen that is found in Escherichia coli O86.
Arun B. Ingle, Chin-Sheng Chao, Wei-Cheng Hung, Kwok-Kong Tony Mong
Asian J. Org. Chem. 2014, 3, No. 8, 870. Read article.
Disilicon ligand: The reaction of N-heterocyclic-carbene-stabilized disilicon with CuCl gave a carbene-stabilized disilicon–copper(I) chloride complex (see figure). The nature of the structure and bonding in this complex was investigated by experimental, spectroscopic, and computational methods. The dynamic complexation behavior of the compound was explored by variable-temperature NMR experiments.
Mingwei Chen, Yuzhong Wang, Yaoming Xie, Pingrong Wei, Robert J. Gilliard, Jr.Nichole A. Schwartz, Henry F. Schaefer, IIIPaul von R. Schleyer, Gregory H. Robinson
Chem. Eur. J. 2014, 20, No. 30, 9208. Read article.
This comprehensive mechanistic study sheds light on the facility of the initial metalation of branched alkyl aryl sulfones and their subsequent formal ortho→α rearrangement. A kinetic investigation, combined with studies aimed at the determination of deuterium KIEs, and crossover experiments, support an intermolecular mechanism for the transmetalation.
Lucie Rehová, Ullrich Jahn
Eur. J. Org. Chem. 2014, No. 21, 4610. Read article.
A new class of functionalized carbon nanotubes synthesized on the basis of in situ deprotected tosylhydrazones and the formation of cyclopropanated products is reported. A different product is obtained with different types of tosylhydrazones. This new class of functionalized carbon nanotubes is analogues to PC60BM materials and can find future use in plastic solar cells or flexible electronics.
Zois Syrgiannis, Caroline Hadad, Maurizio Prato
Eur. J. Org. Chem. 2014, No. 20, 4225. Read article.
No more waste: Supported gold nanoparticles catalyze the coupling of unactivated arenes in O2 without the typical need of iodine oxidants, acids, bases, or additional metal salts in solution to result in a zero-waste synthetic process. This is in contrast to other catalysts that can perform for only a few turnovers and produce large quantities of waste.
Pedro Serna, Avelino Corma
ChemSusChem 2014, 7, No. 8, 2136. Read article.
Hell hath no furan: A simple and effective water extraction method to purify 5-hydroxylmethylfurfural (HMF) obtained from biomass dehydration system is reported. Up to 99 % of the HMF can be recovered and the aqueous solution of HMF can be directly used for further catalytic oxidization reaction to 2,5-furandicarboxylic acid (FDCA) as the sole product. This purification technique allows an integrated process to produce FDCA from fructose via HMF
Guangshun Yi, Siew Ping Teong, Xiukai Li, Yugen Zhang
ChemSusChem 2014, 7, No. 8, 2131. Read article.
Light switches: The combination of a cell-permeable, photocaged ligand and a theophylline riboswitch provided a simple and efficient strategy to control gene expression within bacterial cells by using light. This approach can be used to regulate artificial genetic circuits.
Steven Walsh, Laura Gardner, Alexander Deiters, Gavin J. Williams
ChemBioChem 2014, 15, No. 9, 1346. Read article.
Useful nitrogen-containing heterocycles can be rapidly synthesized from metal-catalyzed regioselective functionalization of enamides. This review discloses the progress made in the development of the direct C-H functionalization of enamides involving efficient and atom-economical routes (see scheme; EWG=electron-withdrawing group).
Nicolas Gigant, Laëtitia Chausset-Boissarie, Isabelle Gillaizeau
Chem. Eur. J. 2014, 20, No. 25, 7548. Read article.
Better together: Two new 8-hydroxyquinoline-appended cyclodextrins are reported (see scheme) and their multifunctional properties are highlighted, including their CuII and ZnII binding abilities, and their capacity to act as antioxidants and antiaggregants.
Valentina Oliveri, Francesco Attanasio, Antonino Puglisi, John Spencer, Carmelo Sgarlata, Graziella Vecchio
Chem. Eur. J. 2014, 20, No. 29, 8954. Read article.
Ideal for bulky substrates: Catalytic behavior of hierarchical MFI zeolites was investigated in annulation reaction of phenols differing in size with methylbutenol and compared with that of medium and large-pore zeolites MFI and BEA.
Maksym V. Opanasenko, Mariya V. Shamzhy, Changbum Jo, Ryong Ryoo, Jirí Čejka
ChemCatChem 2014, 6, No. 7, 1919. Read article.
Magical magnetite: The electrochemical behavior of oleyl-coated Fe3O4 nanoparticles synthesized by chemical co-precipitation is investigated. The modified electrodes exhibit electrochemical behavior in acidic media but not in alkaline media. The results open up new prospects for future mechanistic and analytical studies of magnetite nanoparticles.
Krishnan Murugappan, Debbie S. Silvester, Deeptangshu Chaudhary, Damien W. M. Arrigan
ChemElectroChem 2014, 1, No. 7, 1211. Read article.
We have explored the scope and limitations of N-tetrachlorophthaloyl- (N-TCP) and N-trifluoroacetyl-substituted (N-TFA) galactosamine building blocks for the preparation of chondroitin sulfate oligosaccharides. These synthetic routes provided two disaccharides and two tetrasaccharides with different sulfate distribution patterns.
Giuseppe Macchione, Susana Maza, M. Mar Kayser, José L. de Paz, Pedro M. Nieto
Eur. J. Org. Chem. 2014, No. 18, 3868. Read article.
Dual-site click labeling: A ligand-assisted CuAAC reaction, pyrrolysine-based genetic code expansion strategy, and the PRIME labeling technique were integrated for dual-site click labeling of EGFR at the surface of mammalian cells. This strategy enabled simultaneous installation of a FRET donor–acceptor pair onto the extracellular domains of EGFR, thereby allowing cis-membrane FRET imaging of receptor dynamics.
Yi Yang, Shixian Lin, Wei Lin, Peng R. Chen
ChemBioChem 2014, 15, No. 12, 1738. Read article.
Bond activation by intramolecular interactions of alkynyl carbon with highly Lewis acidic aluminium atoms was observed for functionalised alkenyl-alkynylgermanes. Such mixed germanium–aluminum or –gallium compounds were obtained by hydrometallation of dialkynylgermanes and are promising candidates for secondary reactions such as cyclisation or insertion.
Werner Uhl, Stefan Pelties, Martina Rohling, Jens Tannert
Eur. J. Inorg. Chem. 2014, No. 17, 2809. Read article.
The control of the helix handedness of water-soluble quinoline-based oligoamide foldamers has been investigated by the installation of chiral end groups at either the N or C terminus. This has respectively afforded either quantitative induction of handedness or the ability to separate kinetically locked P and M helices as diastereoisomers.
Simon J. Dawson, Adám Mészáros, Lilla Pethő, Cinzia Colombo, Márton Csékei, András Kotschy, Ivan Huc
Eur. J. Org. Chem. 2014, No. 20, 4265. Read article.
The life of π: Pt-based quinoline and benzothiazole complexes were synthesized with an aim to design drugs with higher affinity for π–π stacking and electrostatic interactions with targeted biomolecules. Fluorescence spectroscopy and molecular modeling led to candidate complexes with significant cytotoxicity toward various tumor cell lines.
Erin S. F. Ma, A. Gerard Daniel, Nicholas P. Farrell
ChemMedChem 2014, 9, No. 6, 1155. Read article.
Two different paths: Phosphonium azolide ionic liquids of interest for CO2 capture applications react with CO2 both through the normal anion channel and, at elevated temperatures, through a previously unrecognized cation channel. The cation channel involves a phosphonium ylide intermediate that is formed due to cation/anion interactions. This channel is suppressed with less-acidic ammonium cations.
Thomas R. Gohndrone, Tae Bum Lee, M. Aruni DeSilva, Mauricio Quiroz-Guzman, William F. Schneider, Joan F. Brennecke
ChemSusChem 2014, 7, No. 7, 1970. Read article.
Brains not Brønsted: Sulfonyl-containing ammonium-based Brønsted acid ionic liquids (ILs) are prepared and used as liquid heterogeneous catalysts for organic reactions under solvent-free conditions. The sulfonyl group endowed these ILs with unique macroscopic phase heterogeneity in the reaction system, ensuring outstanding catalytic activities of the ILs. These catalytic systems are applicable in a wide range of acid-catalyzed reactions.
Amir Taheri, Xiaojuan Pan, Changhui Liu, Yanlong Gu
ChemSusChem 2014, 7, No. 8, 2094. Read article.
More red wine, please: Resveratrol, a signaling protein modulator, can exert off-target effects involving peroxisome proliferator-activated receptors (PPARs). Results from chromatographic and isothermal titration calorimetry experiments indicate that resveratrol and its metabolites bind PPARγ directly, but only resveratrol interacts with PPARα, thus suggesting a new pattern of receptor–ligand recognition.
Enrica Calleri, Giorgio Pochetti, Katina S. S. Dossou, Antonio Laghezza, Roberta Montanari, Davide Capelli, Ellen Prada, Fulvio Loiodice, Gabriella Massolini, Michel Bernier, Ruin Moaddel
ChemBioChem 2014, 15, No. 8, 1154. Read article.
Gold–support synergy: Au nanoparticles supported on Ni–Al layered double hydroxides exhibit high chemoselectivity, recyclability, and reproducibility for the liquid-phase aerobic oxidation of alcohols under base-free or even solvent-free conditions. The synergistic effect between the nanoparticles and the layered double hydroxide support dominates the unique catalytic activity, which is also correlated to the complete ordering of cations in the surface layers.
Jiang Wang, Xianjun Lang, Bao Zhaorigetu, Meilin Jia, Jun Wang, Xiaofang Guo, Jincai Zhao
ChemCatChem 2014, 6, No. 6, 1737. Read article.
More than bricks and mortar: Dibenzo[g,p]chrysenes possessing a variety of substituents were synthesized. Single-crystal X-ray diffraction studies of these compounds revealed that they possess twisted molecular and brickwork packing structures. These structures are useful for their application to carrier transport materials.
Yasuyuki Ueda, Hayato Tsuji, Hideyuki Tanaka, Eiichi Nakamura
Chem. Asian J. 2014, 9, No. 6, 1623. Read article.
For ethylene/ethane separation by PSA, the adsorption properties of [Cu2(2,3-pyrazinedicarboxylate)2(pyrazine)]n were investigated by both the single and binary gas system, which revealed its ethylene selective nature. Moreover, spectroscopic and computational studies suggested the importance of hydrogen bonds in the selective adsorption of ethylene over ethane.
Keisuke Kishida, Yumiko Watanabe, Satoshi Horike, Yoshihiro Watanabe, Yoshikuni Okumura, Yuh Hijikata, Shigeyoshi Sakaki, Susumu Kitagawa
Eur. J. Inorg. Chem. 2014, No. 17, 2747. Read article.
Two new compounds, one with a 3D/3D hetero-interpenetrating diamondoid framework and the other with a homo-interpenetrating pcu network, are synthesized through a one-pot reaction. Their pure phases are obtained by adjusting the metal/ligands ratio. The magnetic properties of the homo-interpenetrating network are investigated.
Xiang-Guang Guo, Wen-Bin Yang, Xiao-Yuan Wu, Lang Lin, Can-Zhong Lu
Eur. J. Inorg. Chem. 2014, No. 15, 2481. Read article.
You never stop learning about film: Post-treatment of micrometer-thick poly(acrylic acid)/poly(allylamine hydrochloride) films with highly interpenetrated film structures produces macroporous films with closed honeycomb-like pores of several micrometers. These macroporous films can be conveniently released from substrates to produce free-standing films with satisfactory mechanical stability.
Xiaoling Chen, Junqi Sun
Chem. Asian J. 2014, 9, No. 8, 2063. Read article.
Metal with mettle: Catalytic metallodrugs are a new compound class with potential for high therapeutic activity and low toxicity. The Cu-GGHYrFK-amide complex was reported earlier to catalytically inactivate stem loop IIb of the HCV internal ribosomal entry site RNA, and to show significant antiviral activity in a cellular HCV replicon assay. Herein we describe our studies focused on understanding the cleavage mechanism and the relationship of catalyst configuration to structural recognition and site-selective cleavage of the structured RNA motif.
Seth S. Bradford, Martin James Ross, Insiya Fidai, James A. Cowan
ChemMedChem 2014, 9, No. 6, 1275. Read article.
Like pinning down an ant: An Ru PNP catalyst provides unprecedented rates of CO2 hydrogenation up to 1 100 000 h−1 (turnover number >200 000) and excellent activity in the dehydrogenation of formic acid in DMF if used with the non-nucleophilic 1,8-diazabicyclo[5.4.0]undec-7-ene base. Unlike amine-based systems, this medium allows us to achieve high formate capacity together with rapid H2 charging and release.
Georgy A. Filonenko, Robbert van Putten, Erik N. Schulpen, Emiel J. M. Hensen, Evgeny A. Pidko
ChemCatChem 2014, 6, No. 6, 1526. Read article.
Two in one: The oxidation of elemental palladium with oleum in the presence of BaCO3 under harsh conditions led to the unprecedented heteroleptic palladate [Pd(HS2O7)2(S3O10)2]4−, which shows a Pd atom coordinated by two different polysulfate species (see figure).
Jörn Bruns, Thorsten Klüner, Mathias S. Wickleder
Chem. Asian J. 2014, 9, No. 6, 1594. Read article.
Matching sodium olivine and tin: An electrochemically converted NaFePO4 olivine cathode and a nanostructured Sn–C anode are combined in an efficient, sodium-ion battery, characterized by a capacity of 150 mAh g−1, a voltage of 3 V and, consequently, a practical energy density estimated to be of the order of 150 Wh kg−1
Ivana Hasa, Jusef Hassoun, Yang-Kook Sun, Bruno Scrosati
ChemPhysChem 2014, 15, No. 10, 2152. Read article.
Just tin time! SnS2 nanoplatelets were incorporated with graphene by using a facile hydrothermal method. Graphene nanosheets act as a heterogeneous dispersing agent to prevent the aggregation of SnS2 nanoplatelets and provide electrically conductive networks, which lead to an improved electrochemical performance for sodium-ion storage (see figure).
Xiuqiang Xie, Dawei Su, Shuangqiang Chen, Jinqiang Zhang, Shixue Dou, Guoxiu Wang
Chem. Asian J. 2014, 9, No. 6, 1611. Read article.
Polyoxometalates, like small pieces of metal oxide, can be dissolved or fixed on a surface to perform homogeneous or heterogeneous catalysis, respectively. Here we exploit the alkaline nature of polyoxoniobates to neutralize nerve agents in both solution and the solid state. Solution studies correlate reaction efficacy to the association of the dissolved polyoxoniobate with its counterions.
Mark K. Kinnan, William R. Creasy, Lauren B. Fullmer, Heidi L. Schreuder-Gibson, May Nyman
Eur. J. Inorg. Chem. 2014, No. 14, 2361. Read article.
Pièce de résistance! Multidrug resistance (MDR) is the main obstacle toward effective anticancer therapy. Herein we report the discovery of two small-molecule 14-3-3 protein–protein interaction inhibitors that promote the translocation of c-Abl and FOXO pro-apoptotic factors into the nucleus and sensitize MDR cancer cells to doxorubicin and the pan-Akt inhibitor GSK690693.
Mattia Mori, Giulia Vignaroli, Ylenia Cau, Jelena Dinić, Richard Hill, Matteo Rossi, David Colecchia, Milica Pešić, Wolfgang Link, Mario Chiariello, Christian Ottmann, Maurizio Botta
ChemMedChem 2014, 9, No. 5, 973. Read article.
Keeping on the ultralow: Quantitative information about the journey of sulfur molecules inside an operating ultralow sulfur diesel reactor is provided. This information coupled with other new insights obtained under realistic industrial conditions is expected to significantly increase the effectiveness of future studies aimed at increasing the efficiency of the ultralow sulfur diesel process. ppmw=parts per million by weight
Tushar V. Choudhary, Kening Gong, Phillipp Ellison, Ayyappan Subbiah
ChemCatChem 2014, 6, No. 6, 1782. Read article.
Great things in small packages: Large-area α-MnO2 nanoflower arrays on flexible substrates are synthesized through a facial template-free electrochemical deposition process. These nanoflower arrays produce an enhanced electrochemical performance in the form of a high specific capacitance with remarkable rate capability and excellent cycling stability.
Wenyao Li, Kaibing Xu, Bo Li, Jianqing Sun, Feiran Jiang, Zhishui Yu, Rujia Zou, Zhigang Chen, Junqing Hu
ChemElectroChem 2014, 1, No. 6, 1003. Read article.
Bent on stability: The nematic liquid-crystal phases formed by bent-core molecules have remarkable properties. This Minireview reports recent progress in stabilizing the nematic phase at accessible temperatures, concentrating on oxadiazole-based materials. It also describes recent measurements of their physical properties, including optical, dielectric, elastic, and flexoelectric coefficients, and electric field effects (see graphic).
Helen F. Gleeson, Sarabjot Kaur, Verena Görtz, Abdel Belaissaoui, Stephen Cowling, John W. Goodby
ChemPhysChem 2014, 15, No. 7, 1251. Read article.
Special effects in 2D: The temperature-dependent Raman spectra of single- and few-layer MoSe2 and WSe2 in the 77–700 K range are reported. Linear variation is observed in the peak positions and widths of the bands arising from contributions of anharmonicity and thermal expansion.
Dattatray J. Late, Sharmila N. Shirodkar, Umesh V. Waghmare, Vinayak P. Dravid, C. N. R. Rao
ChemPhysChem 2014, 15, No. 8, 1592. Read article.
In charge: The influence of the charge relay effects of peptide organic templates on silica mineralization has been investigated. β-Sheet-type peptide shows higher catalytic activity toward the condensation of trimethylsilanol than random-coil peptide (see figure). Silica mineralized on the Val-His-Val-Glu-Val-Ser (VHVEVS) peptide template forms a flat surface, which is affected by the peptide morphology.
Kazuki Murai, Masahiro Higuchi, Tatsuya Kuno, Katsuya Kato
ChemPlusChem 2014, 79, No. 4, 531. Read article.
Control freak: The final product of important multistep electrode reactions, such as the electro-reduction of oxygen, depends on the extent of a surface-catalysed reaction and, therefore, on the nature and coverage of the nanoparticles employed for the electrode modification.
Eduardo Laborda, Christopher C. M. Neumann, Ying Wang, Kristopher R. Ward, Angela Molina, Richard G. Compton
ChemElectroChem 2014, 1, No. 5, 909. Read article.
Simplified complexity! The natural products silvestrol (1) and episilvestrol (2) are translation initiation inhibitors with potent anticancer activity. We report replacing the complex pseudo-sugar moiety at C6 with readily accessible and drug-like moieties. Selected compounds show potent anti-leukemic activity in vitro.
Bill C. Hawkins, Lisa M. Lindqvist, Duong Nhu, Phillip P. Sharp, David Segal, Andrew K. Powell, Michael Campbell, Eileen Ryan, Jennifer M. Chambers, Jonathan M. White, Mark A. Rizzacasa, Guillaume Lessene, David C. S. Huang, Christopher J. Burns
ChemMedChem 2014, 9, No. 7, 1556. Read article.
Sheath shielding: It is shown that if significant adsorption occurs on the sheath used to insulate a microdisc electrode, then it can have a high impact on the measured current–time data because of a considerable shielding effect. Chronoamperograms are simulated as a function of the sheath-to-disc electrode radius ratio and the rate constant for adsorption onto the sheath.
Shaltiel Eloul, Richard G. Compton
ChemElectroChem 2014, 1, No. 5, 917. Read article.
Film star: A new method for drying cholesteric liquid-crystalline cellulose nanocrystal suspensions into solid films avoids phase coexistence and, with an applied circular shear flow, yields unprecedented structural control. The commonly observed mosaic-like structure, with randomly varying orientation of the cholesteric helix axis, is replaced by a macroscopically uniform film with improved optical properties (see figure).
Ji Hyun Park, JungHyun Noh, Christina Schütz, German Salazar-Alvarez, Giusy Scalia, Lennart Bergström, Jan P. F. Lagerwall
ChemPhysChem 2014, 15, No. 7, 1477. Read article.
Pucker up: The gas-phase isomerism of cycloserine and its protonated forms was investigated computationally and experimentally by IR multiphoton dissociation spectroscopy. The isomers of cycloserine show pronounced ring puckering, which generates rich conformeric landscapes (see figure). The relative stability of the various isomers responds to a balance between attractive and repulsive interactions among the functional groups of the molecule.
Caterina Fraschetti, Antonello Filippi, Stefano Borocci, Vincent Steinmetz, Maurizio Speranza
ChemPlusChem 2014, 79, No. 4, 584. Read article.
Arachno compounds: Room-temperature UV photolysis of [Re2(CO)10] with BH3·thf yielded arachno-[(CO)8Re2B2H6], which catalyzed the cyclotrimerization of various internal and terminal alkynes to yield mixtures of 1,3,5- and 1,2,4-substituted benzenes (see figure).
V. P. Anju, Subrat Kumar Barik, Bijnaneswar Mondal, V. Ramkumar, Sundargopal Ghosh
ChemPlusChem 2014, 79, No. 4, 546. Read article.
Paving the way: The successful preparation of biocompatible hybrids by integrating graphene oxide with amphiphilic pillararenes for in vitro Raman and fluorescence dual-mode bioimaging has been carried out (see scheme), thereby paving the way for utilizing these materials in combined cancer diagnostics.
Huacheng Zhang, Xing Ma, Kim Truc Nguyen, Yongfei Zeng, Shuhui Tai, Yanli Zhao
ChemPlusChem 2014, 79, No. 3, 462. Read article.
Non-hinge binding: A novel organometallic protein kinase inhibitor scaffold based on a cyclometalated 1,8-phenanthrolin-7(8 H)-one ligand is reported, which binds to the ATP binding site of the protein kinase Pim1 in an unexpected, unusual non-ATP-mimetic fashion without mimicking the hydrogen-bonding interaction of the adenine nucleobase of ATP.
Kathrin Wähler, Katja Kräling, Holger Steuber, Eric Meggers
ChemistryOpen 2013, 2, No. 5-6, 180. Read article.
Trapped within: We report single-crystal characterization of polymorphs of the ammonium carbamate self-derivative salt of prolinamide, and the first crystal structure of prolinamide and of derived products. This study emphasizes the reactivity of carbonated amines in the solid state and opens perspectives for a systematic study of (solid-state) reactions involving these trapped reactive species.
Anaëlle Tilborg, Steve Lanners, Bernadette Norberg, Johan Wouters
ChemistryOpen 2013, 2, No. 5-6, 194. Read article.
Simple and effective: A facile procedure for monitoring chemical reactions and characterizing compounds dissolved in ionic liquids is described using the MS/MS technique. Separation of species of interest was carried out using internal electronic gate available in electrospray mass spectrometers, instead of chromatography and extraction. The separation was carried out as a fast (milliseconds) and sustainable (no extra solvents) procedure.
Levon L. Khemchyan, Elena A. Khokhlova, Marina M. Seitkalieva, Valentine P. Ananikov
ChemistryOpen 2013, 2, No. 5-6, 208. Read article.
Water purification with β-Bi2O3: A straightforward synthetic procedure for the synthesis of β-Bi2O3 nanoparticles that offers the potential for gram-scale production is presented. The β-Bi2O3 nanoparticles show high photocatalytic activity and stability in the degradation of typical organic water pollutants under visible light irradiation. These nanoparticles might be promising materials for use in novel water purification systems.
Maik Schlesinger, Marcus Weber, Steffen Schulze, Michael Hietschold, Michael Mehring
ChemistryOpen 2013, 2, No. 4, 146. Read article.