Mission Statement

The Asian Chemical Editorial Society (ACES) is an organization of 13 major chemical societies in Asia and the Pacific. It was founded in 2005 as a conglomeration of chemical societies with the mutual aim of creating a modern publishing forum for research in Asia and coordinating future publishing activities.

The participating societies share a commitment to scientific excellence, to publishing ethics, and to the highest standards in publication, which are the basis for the success of Chemistry—An Asian Journal and its associated journals.

Publications

Chemistry—An Asian Journal

A sister journal of Angewandte Chemie and Chemistry—A European Journal

Supporting Organizations: ChemPubSoc Europe, Gesellschaft Deutscher Chemiker (German Chemical Society, GDCh), Federation of Asian Chemical Societies (FACS).

Asian Journal of Organic Chemistry

A sister journal of the European Journal of Organic Chemistry

For the publication of the AsianJOC, ACES is joined by the Korean Society of Organic Synthesis.

Supporting Organization: ChemPubSoc Europe

ACES supports the publication of the ChemPubSoc Europe journals Chemistry—A European Journal, the European Journal of Organic Chemistry, and ChemSusChem.

Asian Journal of Organic Chemistry

Supporting Organization: Federation of Asian Chemical Societies (FACS)

© Wiley-VCH 2015

Journals

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Chem Asian J

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ChemAsianJ for iPad

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Asian J Org Chem

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AsianJOC for iPad

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ChemNanoMat

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Sister
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Angew Chem

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Chem Eur J

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Eur J Org Chem

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Associated
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ChemSusChem

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Chem Rec

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Chin J Chem

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J Chin Chem Soc

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News

Latest Impact Factors

ACES journals have received excellent ratings in the 2014 Journal Citation Reports. Learn more.

Editorials: New Developments

Chemistry - An Asian Journal Theresa Kueckmann
A Reason to Celebrate!
Chem. Asian J. 2015 10, 4.

Asian Journal of Organic ChemistryRichard Threlfall
Something Old, Something New, Something Borrowed, Something Blue
Asian J. Org. Chem. 2015 4, 4.

Asian Journal of Organic ChemistryTheresa Kueckmann, Claire Cobley
ChemNanoMat—A New Journal for Small Science with a Big Impact
ChemNanoMat 2015, 1, 4–8.

 

Research of the DayEditors' Choice: Spotlights

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One-Step Synthesis of [16]Helicene

One-Step Synthesis of [16]Helicene

An aromatic spiral layer: A [16]helicene core was prepared in a single step by sextuple photocyclization from a single-strand arylene–vinylene precursor containing four phenylene and three naphthylene units linked by six vinylene spacers. X-ray crystallographic analysis revealed the triple-layered structure. A new guideline for the design of precursor olefins resulted in the longest helicene synthesized to date.

[Communication]
Kazuyuki Mori, Takashi Murase, Makoto Fujita
Angew. Chem. Int. Ed. 2015, 54, No. 23, 6847. Read article.

Responsive Inverse Opal Hydrogels for the Sensing of Macromolecules

Responsive Inverse Opal Hydrogels for the Sensing of Macromolecules

A successful marriage: The combination of smart hydrogels and inverse opal structures unites simplicity with efficacy for sensing macromolecules. While the inverse opal structure provides structural color and a large accessible interface for binding, the induced phase transition of the analyte-responsive hydrogel produces strong optical effects. The resulting spectral shifts can surpass 100 nm and are easily detected.

[Communication]
Jean-Philippe Couturier, Martin Sütterlin, André Laschewsky, Cornelia Hettrich, Erik Wischerhoff
Angew. Chem. Int. Ed. 2015, 54, No. 22, 6641. Read article.

Fast and Efficient Synthesis of Z‐Enol‐γ‐Lactones through a Cycloisomerization Reaction of β‐Hydroxy‐γ‐Alkynoic Acids Catalyzed by Copper(I) under Microwave Heating in Water

[Full Paper]
José G. López‐Cortés, R. Alfredo Toscano, Morelia E. López‐Reyes, Cecilio Alvarez‐Toledano
Asian Journal of Organic Chemistry 2015, 4, No. 6, 545. Read article.

Recent Advances in the Transition‐Metal‐Catalyzed Enantioselective Synthesis of Silicon‐Stereogenic Organosilanes

[Focus Review]
Ryo Shintani
Asian Journal of Organic Chemistry 2015, 4, No. 6, 510. Read article.

50 Years in the Sun of Bürgenstock—On the Success Factors of a Famous Conference

50 Years in the Sun of Bürgenstock—On the Success Factors of a Famous Conference

The secret of success: This year the famous “Bürgenstock Conference” will take place for the 50th time. This conference has become internationally one of the, if not the, most highly regarded conference in chemistry, chemical biology, and physical chemistry. What are the success factors of this conference? These as well as a number of perhaps more hidden figures and facts are discussed.

[Essay]
Klaus Müller
Angew. Chem. Int. Ed. 2015, 54, No. 17, 5012. Read article.

A Synthetic Erectile Optogenetic Stimulator Enabling Blue-Light-Inducible Penile Erection

A Synthetic Erectile Optogenetic Stimulator Enabling Blue-Light-Inducible Penile Erection

A bolt from the blue: A synthetic designer guanylate cyclase producing a blue-light-inducible surge of the second messenger cyclic guanosine monophosphate (cGMP) in mammalian cells was used as an erectile optogenetic stimulator (EROS). Blue-light-dependent penile erection associated with occasional ejaculation was triggered in male rats by simple illumination of EROS-transfected corpus cavernosum with a portable commercial light-therapy device.

[Communication]
Taeuk Kim, Marc Folcher, Marie Doaud-El Baba, Martin Fussenegger
Angew. Chem. Int. Ed. 2015, 54, No. 20, 5933. Read article.

Solvent-Enabled Nonenyzmatic Sugar Production from Biomass for Chemical and Biological Upgrading

Solvent-Enabled Nonenyzmatic Sugar Production from Biomass for Chemical and Biological Upgrading

Super phenolic solvents: Biomass-derived carbohydrates represent an attractive source of renewable carbon due to their many chemical and biological conversion routes to fuels and chemicals. In a nonenzymatic biomass deconstruction process for producing carbohydrates, separating a mixture of γ-valerolactone (GVL) and water used in the process is a key step. We demonstrate that phenolic solvents are highly effective at separating GVL and can be used to detoxify the biomass-derived mixture for fermentation.

[Communication]
Jeremy S. Luterbacher, David Martin Alonso, Jacqueline M. Rand, Ydna M. Questell-Santiago, Jher Hau Yeap, Brian F. Pfleger, James A. Dumesic
ChemSusChem 2015, 8, No. 8, 1317. Read article.

Expression, Receptor Binding, and Biophysical Characterization of Guinea Pig Insulin desB30: A Monomeric Insulin Variant

Expression, Receptor Binding, and Biophysical Characterization of Guinea Pig Insulin desB30: A Monomeric Insulin Variant

Cute, cuddly insulin: Guinea pig desB30 insulin was expressed in Saccharomyces cerevisiae, and its affinities for the human insulin receptor A and IGF-I receptor were measured for the first time in scintillation proximity assays. Small-angle X-ray scattering and analytical ultracentrifugation studies confirmed that GI does not form dimers or hexamers.

[Full Paper]
Ebbe Engholm, Thomas H. Hansen, Eva Johansson, Holger M. Strauss, Tine N. Vinther, Knud J. Jensen, Frantisek Hubálek, Thomas B. Kjeldsen
ChemBioChem 2015, 16, No. 6, 954. Read article.

Enantioselective Sulfa-Michael Addition to α,β-Unsaturated γ-Oxoesters Catalyzed by a Metal-Templated Chiral Brønsted Base

Enantioselective Sulfa-Michael Addition to α,β-Unsaturated γ-Oxoesters Catalyzed by a Metal-Templated Chiral Brønsted Base

Low loader: A chiral-at-metal octahedral iridium(III) complex serves as a low-loading chiral Brønsted base catalyst for an enantioselective Michael addition. This work highlights the manifold opportunities provided by this metal-templated design in which the metal exerts a purely structural role whereas catalysis is mediated through the organic ligand sphere (metal-templated organocatalysis).

[Communication]
Xiaobing Ding, Huihua Lin, Lei Gong, Eric Meggers
Asian J. Org. Chem. 2015, 4, No. 5, 434. Read article.

Improving Cell-Free Protein Synthesis through Genome Engineering of Escherichia coli Lacking Release Factor 1

Improving Cell-Free Protein Synthesis through Genome Engineering of Escherichia coli Lacking Release Factor 1

Cell-free synthetic biology: We have developed a high-yielding, cell-free protein synthesis (CFPS) platform for site-specific incorporation of non-standard amino acids (NSAAs) into proteins. Multiplex automated genome engineering (MAGE) was used to construct RF1-deficient strains with improved performance, thereby opening new avenues for using cell-free synthetic biology for synthetic chemistry.

[Full Paper]
Seok Hoon Hong, Yong-Chan Kwon, Rey W. Martin, Benjamin J. Des Soye, Alexandra M. de Paz, Kirsten N. Swonger, Ioanna Ntai, Neil L. Kelleher, Michael C. Jewett
ChemBioChem 2015, 16, No. 5, 844. Read article.

A Facile Route to Bis(pyridyl-1,3,5-triazine) Ligands with Fluorescing Properties

A Facile Route to Bis(pyridyl-1,3,5-triazine) Ligands with Fluorescing Properties

Several bis(pyridyl-1,3,5-triazine) (dpt) ligands are prepared via Stille coupling with yields and scope of application superior to known trimerisation procedures. Ditopic ligands with different spacers are prepared and incorporation of p- and m-substituted phenyl rings enable access to different isomers. The absorption and emission properties can be tuned using oligothiophene spacers.

[Full Paper]
Matthias F. Geist, Daniel Chartrand, Mihaela Cibian, Fabian Zieschang, Garry S. Hanan, Dirk G. Kurth
Eur. J. Org. Chem. 2015, No. 11, 2366. Read article.

An Efficient and Green Synthesis of 1-Indanone and 1-Tetralone via Intramolecular Friedel–Crafts Acylation Reaction

An Efficient and Green Synthesis of 1-Indanone and 1-Tetralone via Intramolecular Friedel–Crafts Acylation Reaction

Unper-terb-ed: Terbium triflate catalyzes the intramolecular Friedel–Crafts acylation of 3-arylpropanoic and 4-arylbutanoic acids in ionic liquids under microwave irradiation.

[Full Paper]
Phuong Hoang Tran, Vy Hieu Huynh, Poul Erik Hansen, Duy-Khiem Nguyen Chau, Thach Ngoc Le
Asian J. Org. Chem. 2015, 4, No. 5, 482. Read article.

Water Soluble CuInSe2 Nanoplates: Controlled Synthesis, Photoelectric Response and Electrocatalytic Reduction of Polysulfides

[Full Paper]
Rongrong Qi, Jiantao Zai, Xiangyang Wu, Yanping Yuan, Fang Dai, Wenlong Chen, Qi Zhu, Xuefeng Qian
ChemNanoMat 2015, 1, No. 1, 52. Read article.

Rapid Sonochemical Synthesis of Luminescent and Paramagnetic Copper Nanoclusters for Bimodal Bioimaging

[Communication]
Quan Lin, Yuanqing Sun, Hao Cheng, Chuanxi Wang, Chi Zhang
ChemNanoMat 2015, 1, No. 1, 27. Read article.

Catalyst Activation, Deactivation, and Degradation in Palladium-Mediated Negishi Cross-Coupling Reactions

Catalyst Activation, Deactivation, and Degradation in Palladium-Mediated Negishi Cross-Coupling Reactions

Catalytic complexity: The Pd catalyst used in Negishi cross-coupling reactions shows an unexpected heterogeneity and complexity. Among the various species observed in solution, heterobimetallic Pd–Zn complexes are of particular interest (see figure). These species also seem key to understanding the kinetics of Negishi cross-coupling reactions. S-PHOS=2-dicyclohexylphosphino-2',6'-dimethoxybiphenyl.

[Full Paper]
Katharina Böck, Julia E. Feil, Konstantin Karaghiosoff, Konrad Koszinowski
Chem. Eur. J. 2015, 21, No. 14, 5548. Read article.

Orthogonal Translation Meets Electron Transfer: In Vivo Labeling of Cytochrome c for Probing Local Electric Fields

Orthogonal Translation Meets Electron Transfer: In Vivo Labeling of Cytochrome c for Probing Local Electric Fields

Orthogonal translation meets electron transfer: We have site-specifically incorporated genetically encoded p-cyanophenylalanine into cytochrome c as a noninvasive reporter for probing local electric fields by taking advantage of the vibrational Stark effect (VSE).

[Communication]
Jan Völler, Hernan Biava, Beate Koksch, Peter Hildebrandt, Nediljko Budisa
ChemBioChem 2015, 16, No. 5, 742. Read article.

Designing New Analogs for Streamlining the Structure of Cytotoxic Lamellarin Natural Products

Designing New Analogs for Streamlining the Structure of Cytotoxic Lamellarin Natural Products

Find a library near you: A library of 59 systematically designed analogs of lamellarins were constructed, including those previously inaccessible by the currently available total synthetic strategies due to the presence of the catechol moieties. In conjunction with the 25 parent lamellarins, their structure was streamlined for both cytotoxicity against a panel of cancer cell lines and lipophilic nature.

[Full Paper]
Kassrin Tangdenpaisal, Rattana Worayuthakarn, Supatra Karnkla, Poonsakdi Ploypradith, Pakamas Intachote, Suchada Sengsai, Busakorn Saimanee, Somsak Ruchirawat, Montakarn Chittchang
Chem. Asian J. 2015, 10, No. 4, 925. Read article.

Current Technologies, Economics, and Perspectives for 2,5-Dimethylfuran Production from Biomass-Derived Intermediates

Current Technologies, Economics, and Perspectives for 2,5-Dimethylfuran Production from Biomass-Derived Intermediates

Biomass to valuable feedstock: A concise and up-to-date analysis of 2,5-dimethylfuran (DMF) production technologies and its further upgrade into p-xylene (pX) is given with critical discussion on catalytic systems, mechanistic insight, and process economics. The chemistry detailed in this review will guide researchers to develop more practical catalytic processes that enable the economic production of biorenewable DMF and pX.

[Minireview]
Basudeb Saha, Mahdi M. Abu-Omar
ChemSusChem 2015, 8, No. 7, 1133. Read article.

Carbon-Supported Base Metal Nanoparticles: Cellulose at Work

Carbon-Supported Base Metal Nanoparticles: Cellulose at Work

Mutually beneficial: Pyrolysis under inert conditions of base-metal-salt-loaded (CuII, NiII, CoII or FeIII) microcrystalline cellulose spheres gives homogeneously distributed carbon-supported base metal nanoparticles. Cellulose is converted into an amorphous carbon, which concurrently acts both as support and reductant. The nickel, cobalt, or iron nanoparticles catalyze the graphitization of the amorphous carbon support.

[Communication]
Jacco Hoekstra, Marjan Versluijs-Helder, Edward J. Vlietstra, John W. Geus, Leonardus W. Jenneskens
ChemSusChem 2015, 8, No. 6, 985. Read article.

Governing Chemistry of Cellulose Hydrolysis in Supercritical Water

Governing Chemistry of Cellulose Hydrolysis in Supercritical Water

Just add water: A reaction mechanism for cellulose hydrolysis that can explain the huge selectivity of biomass hydrolysis in supercritical water is presented. The model of the reaction mechanism has been validated by several experiments carried out in a continuous pilot plant capable at various conditions. It was found that the proton and hydroxide anion concentration in the medium due to water dissociation (represented by the ionic product of water, Kw) is the determining factor in the selectivity of the process.

[Full Paper]
Danilo A. Cantero, M. Dolores Bermejo, M. José Cocero
ChemSusChem 2015, 8, No. 6, 1026. Read article.

High Affinity Fluorescent Ligands for the Estrogen Receptor

High Affinity Fluorescent Ligands for the Estrogen Receptor

Dual click reactions have facilitated hydrophobic tagging of selective estrogen receptor modulators (SERMs). Raloxifene conjugation with fluorescent dyes afforded fluorescent ER with affinities superior to estradiol. These stains accumulate in ER expressing cells at low nanomolar concentrations and molecular dynamics simulations suggest dye–ER associations via helix 12 contacts.

[Full Paper]
Frank Abendroth, Marthe Solleder, Dorothea Mangoldt, Pia Welker, Kai Licha, Marcus Weber, Oliver Seitz
Eur. J. Org. Chem. 2015, No. 10, 2157. Read article.

Dispersed Gold Nanoparticles Supported in the Pores of Siliceous Mesocellular Foam: A Catalyst for Cycloisomerization of Alkynoic Acids to γ-Alkylidene Lactones

Dispersed Gold Nanoparticles Supported in the Pores of Siliceous Mesocellular Foam: A Catalyst for Cycloisomerization of Alkynoic Acids to γ-Alkylidene Lactones

An electrochemical method for generating heterogeneously supported AuI thiolates that can be reduced to highly active Au nanoparticles by subsequent treatment with NaBH4 is described. The corresponding Au nanocatalyst was applied in the cycloisomerization of a set of alkynoic acids into the corresponding γ-alkylidene lactones in high yields under mild conditions.

[Full Paper]
Kristofer Eriksson, Oscar Verho, Leif Nyholm, Sven Oscarsson, Jan-E. Bäckvall
Eur. J. Org. Chem. 2015, No. 10, 2250. Read article.

Stimuli-Responsive Cyclopenta[ef]heptalenes: Synthesis and Optical Properties

Stimuli-Responsive Cyclopenta[ef]heptalenes: Synthesis and Optical Properties

Cyclopenta[ef]heptalenes 4ac, prepared by annulation of 3-formylguaiazulene (1), revealed a stimuli-responsive behavior upon treatment with strong acids. 1D and 2D NMR spectroscopy indicated that protonation occurred on C-6, while photoacid titrations demonstrated that the reported tricyclic systems can serve as efficient visible sensitizers of UV-activated photoacid generators (PAGs).

[Full Paper]
Ebrahim H. Ghazvini Zadeh, Adam W. Woodward, David Richardson, Mykhailo. V. Bondar, Kevin D. Belfield
Eur. J. Org. Chem. 2015, No. 10, 2271. Read article.

Versatile Syntheses of Hemi-Cryptophanes and a Metallo-Cryptophane from a Hexa-Functionalized C3v-Symmetrical Tribenzotriquinacene (TBTQ) Derivative

Versatile Syntheses of Hemi-Cryptophanes and a Metallo-Cryptophane from a Hexa-Functionalized C3v-Symmetrical Tribenzotriquinacene (TBTQ) Derivative

Geometry matters! Three different cage molecules 9, 12 and 15, were prepared from the same hexafunctional concave-shape tribenzotriquinacene (TBTQ) derivative 2 a via different types of capping reactions involving various TBTQ-based cavitands. The results demonstrate that the rigid geometry of the TBTQ skeleton renders them highly promising candidates for the construction of extended supramolecular complexes or assemblies.

[Full Paper]
Jun Wei, Zhi-Min Li, Xiao-Jie Jin, Xiao-Jun Yao, Xiao-Ping Cao, Hak-Fun Chow, Dietmar Kuck
Chem. Asian J. 2015, 10, No. 5, 1150. Read article.

Mechanosensitive Membrane Probes

Mechanosensitive Membrane Probes

Lobsters, flippers, disorder, tension, and potential: The origins of the concept of mechanosensitive membrane probes—from fishmarket and scuba diving to the chemistry of vision, mechanochromic organic materials, and mechanosensitive channels—are briefly reviewed (see scheme).

[Concept]
Marta Dal Molin, Quentin Verolet, Saeideh Soleimanpour, Stefan Matile
Chem. Eur. J. 2015, 21, No. 16, 6012. Read article.

Looking for Efficient G-Quadruplex Ligands: Evidence for Selective Stabilizing Properties and Telomere Damage by Drug-Like Molecules

Looking for Efficient G-Quadruplex Ligands: Evidence for Selective Stabilizing Properties and Telomere Damage by Drug-Like Molecules

A great quad workout: Drug-like compounds that show specific G-quadruplex thermal stabilizing effects and the capacity to induce telomeric damage in cancer cells were identified as promising leads for the development of more potent and selective ligands with anticancer activity.

[Full Paper]
Bruno Pagano, Jussara Amato, Nunzia Iaccarino, Chiara Cingolani, Pasquale Zizza, Annamaria Biroccio, Ettore Novellino, Antonio Randazzo
ChemMedChem 2015, 10, No. 4, 640. Read article.

Selective Inhibitors of Glutathione Transferase P1 with Trioxane Structure as Anticancer Agents

Selective Inhibitors of Glutathione Transferase P1 with Trioxane Structure as Anticancer Agents

Peroxides in tumor defense: A dozen cyclic peroxides were prepared by singlet oxygen ene reaction. Investigation of these compounds against tumor-relevant glutathione transferase P1 (GSTP1) revealed Ki values in the low micromolar range. Some inhibitors showed high selectivity for GSTP1 over other GST classes. These findings have strong implications for medicinal chemistry strategies to improve the activity of antitumor drugs.

[Full Paper]
Maria Bräutigam, Nicole Teusch, Tobias Schenk, Miriam Sheikh, Rocky Z. Aricioglu, Swantje H. Borowski, Jörg-Martin Neudörfl, Ulrich Baumann, Axel G. Griesbeck, Markus Pietsch
ChemMedChem 2015, 10, No. 4, 629. Read article.

Polyoxometalate-Mediated One-Pot Synthesis of Pd Nanocrystals with Controlled Morphologies for Efficient Chemical and Electrochemical Catalysis

Polyoxometalate-Mediated One-Pot Synthesis of Pd Nanocrystals with Controlled Morphologies for Efficient Chemical and Electrochemical Catalysis

Single-crystalline Pd nanocrystals with controlled shapes and sizes were synthesized by a polyoxometalate-mediated one-pot aqueous synthesis method. The prepared Pd nanocrystals exhibited enhanced catalytic properties toward electrochemical and chemical reactions (see figure).

[Full Paper]
Dongheun Kim, Ji Hyun Seog, Minjune Kim, MinHo Yang, Eleanor Gillette, Sang Bok Lee, Sang Woo Han
Chem. Eur. J. 2015, 21, No. 14, 5387. Read article.

Xylella fastidiosa Esterase Rather than Hydroxynitrile Lyase

Xylella fastidiosa Esterase Rather than Hydroxynitrile Lyase

Unmasking XfHNL activity: We demonstrate that the product of the gene SCJ21.16 (XFa0032) from X. fastidiosa encodes a protein with esterase activity. Sequence alignment, docking simulations and activity assays support this. Our findings could contribute to elucidating a common ancestor of esterases and hydroxynitrile lyases with an α/β-hydrolase fold.

[Full Paper]
Guzman Torrelo, Fayene Zeferino Ribeiro de Souza, Emanuel Carrilho, Ulf Hanefeld
ChemBioChem 2015, 16, No. 4, 625. Read article.

Design and Synthesis of a MAO-B-Selectively Activated Prodrug Based on MPTP: A Mitochondria-Targeting Chemotherapeutic Agent for Treatment of Human Malignant Gliomas

Design and Synthesis of a MAO-B-Selectively Activated Prodrug Based on MPTP: A Mitochondria-Targeting Chemotherapeutic Agent for Treatment of Human Malignant Gliomas

Specificity is key: We developed a MAO-B-activated prodrug, MP-MUS, for the treatment of brain gliomas. MP-MUS is nontoxic, and can be selectively oxidized by MAO-B, which is overexpressed in glioma cells, to form toxic P+-MUS. P+-MUS translocates inside mitochondria passively and alkylates fragile mitochondrial DNA, leading to specific apoptosis of glioma cells, but not normal cells.

[Full Paper]
Martyn A. Sharpe, Junyan Han, Alexandra M. Baskin, David S. Baskin
ChemMedChem 2015, 10, No. 4, 621. Read article.

Electrochemical Pretreatment of Amino-Carbon Nanotubes on Graphene Support as a Novel Platform for Bilirubin Oxidase with Improved Bioelectrocatalytic Activity towards Oxygen Reduction

Electrochemical Pretreatment of Amino-Carbon Nanotubes on Graphene Support as a Novel Platform for Bilirubin Oxidase with Improved Bioelectrocatalytic Activity towards Oxygen Reduction

Graphene support group: The electrochemical pretreatment of amino-carbon nanotubes (CNTs) on a graphene support in an alkaline solution was used to produce -NHOH as hydrophilic functional groups for the efficient immobilization of bilirubin oxidase, which was then used in the mediator-less direct electrocatalytic reduction of O2 to water with an onset potential of 0.81 V vs. NHE and a peak current density of 2.3 mA cm−2

[Communication]
Aso Navaee, Abdollah Salimi , Fereydoon Jafari
Chem. Eur. J. 2015, 21, No. 13, 4949. Read article.

Hydrophobic Mesoporous Poly(ionic liquid)s towards Highly Efficient and Contamination-Resistant Solid-Base Catalysts

Hydrophobic Mesoporous Poly(ionic liquid)s towards Highly Efficient and Contamination-Resistant Solid-Base Catalysts

Good for Knoevenagel-type reactions: Mesoporous poly(ionic liquid)s-derived solid-base catalysts are prepared, characterized, and evaluated for catalysis. They possess high ionic-liquid-related active species, large surface area, superior hydrophobicity with good substrate compatibility, and good resistance to CO2/H2O contamination.

[Full Paper]
Xiaochen Wang, Jing Li, Guojian Chen, Zengjing Guo, Yu Zhou, Jun Wang
ChemCatChem 2015, 7, No. 6, 993. Read article.

Light-Gated Molecular Brakes Based on Pentiptycene-Incorporated Azobenzenes

Light-Gated Molecular Brakes Based on Pentiptycene-Incorporated Azobenzenes

Braking pad: Three azobenzene derivatives that differed in their terminal substituent were investigated as molecular brakes, in which the rigid H-shaped pentiptycene group functioned as a rotor and the dinitrophenyl group as a brake pad. They are superior to the stilbene counterparts in the on-off switching efficiency.

[Full Paper]
Wei Shyang Tan, Po-Ya Chuang, Chia-Huei Chen, Chetti Prabhakar, Shing-Jong Huang, Shou-Ling Huang, Yi-Hung Liu, Ying-Chih Lin, Shie-Ming Peng, Jye-Shane Yang
Chem. Asian J. 2015, 10, No. 4, 989. Read article.

Ordered Hexagonal Mesoporous Aluminosilicates and their Application in Ligand-Free Synthesis of Secondary Amines

Ordered Hexagonal Mesoporous Aluminosilicates and their Application in Ligand-Free Synthesis of Secondary Amines

Get hexed! Mesoporous aluminosilicates were successfully synthesized and applied as ligand, base-free heterogeneous catalysts for C-N bond formation between benzyl alcohol and aniline for various N-benzyl secondary amines with excellent activity and selectivity.

[Communication]
Pavuluri Srinivasu, Dupati Venkanna, Mannepalli Lakshmi Kantam, Jing Tang, Suresh K. Bhargava, Ali Aldalbahi, Kevin C.-W. Wu, Yusuke Yamauchi
ChemCatChem 2015, 7, No. 5, 747. Read article.

Improving Oxygen Electrochemistry through Nanoscopic Confinement

Improving Oxygen Electrochemistry through Nanoscopic Confinement

Nanostructuring catalysts: Density functional theory calculations show that well-defined reaction geometries substantially improve the activity of RuO2 catalysts for electrochemical oxygen evolution. Enhanced efficiency is primarily due to hydrogen bonding, which breaks the previously limiting energetic scaling relationships of the reaction intermediates.

[Communication]
Andrew D. Doyle, Joseph H. Montoya, Aleksandra Vojvodic
ChemCatChem 2015, 7, No. 5, 738. Read article.

Catalytic Properties of Unsupported Palladium Nanoparticle Surfaces Capped with Small Organic Ligands

Catalytic Properties of Unsupported Palladium Nanoparticle Surfaces Capped with Small Organic Ligands

Put a feather in your cap! This Minireview summarizes a variety of intriguing catalytic studies accomplished by employing unsupported, either solubilized or freely mobilized, and small organic ligand-capped palladium nanoparticles as catalysts. The nanoparticle catalysts are grouped depending on the type of surface stabilizers with reactive head groups including thiolate, phosphine, amine, and alkyl azide.

[Minireview]
Diego J. Gavia, Young-Seok Shon
ChemCatChem 2015, 7, No. 6, 892. Read article.

Two Successive C2 Losses from C86 Fullerene upon Chlorination with the Formation of Non-classical C84Cl30 and C82Cl30

Two Successive C2 Losses from C86 Fullerene upon Chlorination with the Formation of Non-classical C84Cl30 and C82Cl30

Cage shrinkage in IPR C86 fullerene (isomer 16) occurs in the course of high-temperature chlorination. Single-crystal X-ray study revealed the formation of non-classical C84Cl30 and C82Cl30 containing one and two heptagons, respectively (shown in blue) in the carbon cages. Thus, two successive C2 losses (C2Ls) are well documented for the starting, intermediate, and final structures involved in this forked skeletal transformation.

[Communication]
Tao Wei, Shangfeng Yang, Erhard Kemnitz, Sergey I. Troyanov
Chem. Asian J. 2015, 10, No. 3, 559. Read article.

Evaluation of tert-Butyl Isosteres: Case Studies of Physicochemical and Pharmacokinetic Properties, Efficacies, and Activities

Evaluation of tert-Butyl Isosteres: Case Studies of Physicochemical and Pharmacokinetic Properties, Efficacies, and Activities

The alternative scene: Given how common the tert-butyl group is in medicinal chemistry, we set out to explore some isosteric alternatives in hopes of identifying motifs that circumvent the common drawbacks imparted by tert-butyl groups, such as increased lipophilicity and lower metabolic stability.

[Full Paper]
Matthias V. Westphal, Bernd T. Wolfstädter, Jean-Marc Plancher, John Gatfield, Erick M. Carreira
ChemMedChem 2015, 10, No. 3, 461. Read article.

Reactivity of Dinitrogen Bound to Mid- and Late-Transition-Metal Centers

Reactivity of Dinitrogen Bound to Mid- and Late-Transition-Metal Centers

Mid- and late-transition metals are excellent platforms for enabling the reactivity of dinitrogen. This microreview gives an overview of the many reactions in which N2 is cleaved or forms new bonds with electrophiles or radicals. These reactions occur under ambient conditions, and some of them, such as the formation of ammonia or silylamines, are even catalytic.

[Microreview]
Nitesh Khoenkhoen, Bas de Bruin, Joost N. H. Reek, Wojciech I. Dzik
Eur. J. Inorg. Chem. 2015, No. 4, 567. Read article.

Synthesis, Structures and Thermal Decomposition of Monomeric Aluminium, Gallium and Indium Silylphosphanides

Synthesis, Structures and Thermal Decomposition of Monomeric Aluminium, Gallium and Indium Silylphosphanides

A series of new N-heterocyclic carbene (NHC)-stabilized monomeric metal silylphosphanides of aluminium, gallium and indium were characterized through single-crystal X-ray diffraction and their structural and thermal properties are described.

[Full Paper]
Manuel Kapitein, Carsten von Hänisch
Eur. J. Inorg. Chem. 2015, No. 5, 837. Read article.

Homoleptic and Heteroleptic Ruthenium(II) Complexes Based on 2,6-Bis(quinolin-2-yl)pyridine Ligands – Multiple-Charged-State Modules for Potential Density Memory Storage

Homoleptic and Heteroleptic Ruthenium(II) Complexes Based on 2,6-Bis(quinolin-2-yl)pyridine Ligands – Multiple-Charged-State Modules for Potential Density Memory Storage

The ligands diethyl 2,2'-(pyridine-2,6-diyl)bis(quinolone-4-carboxylate) (L2) and 2,6-bis(4-methylquinolin-2-yl)pyridine (L1) were used to prepare the homoleptic [Ru(L1)2][PF6]2 (RU1) and heteroleptic [Ru(L1)(L2)][PF6]2 (RU2) complexes. Electrochemistry experiments showed that the complexes can hold up to five electrons reversibly.

[Full Paper]
Ion Marin, Constantin Turta, Andrew C. Benniston, Ross W. Harrington, William Clegg
Eur. J. Inorg. Chem. 2015, No. 5, 786. Read article.

Bifunctional N-Heterocyclic Carbene Ferrocenyl Ligands – Synthesis and Palladium(II) Complexes

Bifunctional N-Heterocyclic Carbene Ferrocenyl Ligands – Synthesis and Palladium(II) Complexes

Two ferrocenylimidazolium tetrafluoroborate salts, precursors of new ferrocenylimidazol-2-ylidene bifunctional ligands, and the corresponding palladium(II) complexes have been prepared for the first time.

[Full Paper]
Pauline Loxq, Jean-Claude Daran, Eric Manoury, Rinaldo Poli, Agnès Labande
Eur. J. Inorg. Chem. 2015, No. 4, 609. Read article.

Experimental Charge Density Evidence for Pnicogen Bonding in a Crystal of Ammonium Chloride

Experimental Charge Density Evidence for Pnicogen Bonding in a Crystal of Ammonium Chloride

The ties that bind: Chemical binding in crystalline ammonium chloride was studied by using a topological analysis of electron density function derived from high-resolution X-ray diffraction. Supported by periodic quantum chemical calculations, it provided experimental evidence for weak σ-hole bonds (1.5 kcal mol−1) that involve ammonium cations in a crystal (see figure). This type of supramolecular interaction is even more numerous than now appears.

[Article]
Yulia V. Nelyubina, Alexander A. Korlyukov, Konstantin A. Lyssenko
ChemPhysChem 2015, 16, No. 3, 676. Read article.

Single-Molecule Methods to Study Membrane Receptor Oligomerization

Single-Molecule Methods to Study Membrane Receptor Oligomerization

Singles' party: Single-molecule techniques suitable for studying the oligomerization of membrane receptors are reviewed: photobleaching, Förster resonance energy transfer, localization microscopy and co-tracking. Experimental requirements, benefits and difficulties are discussed and biological applications are highlighted.

[Minireview]
Franziska Fricke, Marina S. Dietz, Mike Heilemann
ChemPhysChem 2015, 16, No. 4, 713. Read article.

High Accuracy of Karplus Equations for Relating Three-Bond J Couplings to Protein Backbone Torsion Angles

High Accuracy of Karplus Equations for Relating Three-Bond J Couplings to Protein Backbone Torsion Angles

The right match: 3JHNHα and 3JC'C' couplings both are related to protein backbone dihedral angles φ through Karplus equations. However, the relation between 3JHNHα and φ is indirect as it relies on the unknown exact position of backbone hydrogens, making 3JC'C' the better reporter for φ.

[Article]
Fang Li, Jung Ho Lee, Alexander Grishaev, Jinfa Ying, Ad Bax
ChemPhysChem 2015, 16, No. 3, 572. Read article.

Ultra-Thin Hollow Carbon Nanospheres for Pseudocapacitive Sodium-Ion Storage

Ultra-Thin Hollow Carbon Nanospheres for Pseudocapacitive Sodium-Ion Storage

Thin-skinned: Ultra-thin hollow carbon nanospheres (UTH-CNs) are fabricated as anodes for asymmetric sodium-ion storage pseudocapacitors. The pseudocapacitors based on UTH-CNs and commercially available porous carbon cathodes exhibit the most favorable performance metrics yet reported for asymmetric sodium-ion storage pseudocapacitors.

[Article]
Young Soo Yun, Se Youn Cho, Haegyeom Kim, Hyoung-Joon Jin, Kisuk Kang
ChemElectroChem 2015, 2, No. 3, 359. Read article.

N-Substituted Phenothiazine Derivatives: How the Stability of the Neutral and Radical Cation Forms Affects Overcharge Performance in Lithium-Ion Batteries

N-Substituted Phenothiazine Derivatives: How the Stability of the Neutral and Radical Cation Forms Affects Overcharge Performance in Lithium-Ion Batteries

Redox shuttles are electrolyte additives that can prevent overcharge in batteries. They travel between the anode and cathode in their neutral and oxidized forms, mitigating excess current and stabilizing cell voltage. However, if the neutral or radical cation form of the shuttle decomposes, products can form that no longer protect the battery from overcharge, as is observed in the case of N-tert-butylphenothiazine.

[Article]
Kishore Anand Narayana, Matthew D. Casselman, Corrine F. Elliott, Selin Ergun, Sean R. Parkin, Chad Risko, Susan A. Odom
ChemPhysChem 2015, 16, No. 6, 1179. Read article.

Preparation, Formation Mechanism, and Photoresponse Properties of GeSe Microtubes with a Rectangular Cross Section

Preparation, Formation Mechanism, and Photoresponse Properties of GeSe Microtubes with a Rectangular Cross Section

Controlled growth: A solution approach for the fabrication of GeSe single-crystalline microtubes with rectangular cross sections has been developed, and the GeSe microtubes have a growth axis in the [010] direction and diameters in the range of 1–2 μm (see figure). Clear photoresponsive behavior is recorded for the as-synthesized GeSe microtubes.

[Full Paper]
Liang Shi, Yanan Li, Yumei Dai
ChemPlusChem 2015, 80, No. 3, 630. Read article.

Delivery of Single Nanoparticles from Nanopipettes under Resistive-Pulse Control

Delivery of Single Nanoparticles from Nanopipettes under Resistive-Pulse Control

Accurate delivery: The combination of resistive-pulse technique and scanning ion-conductance microscopy (SICM) can be used for localized delivery of nanoparticles from nanopipettes.

[Communication]
Yixian Wang, Huijing Cai, Michael V. Mirkin
ChemElectroChem 2015, 2, No. 3, 343. Read article.

Voltammetry of Layered Black Phosphorus: Electrochemistry of Multilayer Phosphorene

Voltammetry of Layered Black Phosphorus: Electrochemistry of Multilayer Phosphorene

Black is back: Layered black phosphorus crystals (multilayer phosphorene) is prepared by chemical vapor deposition method. The black phosphorus exhibits inherent electrochemistry in the sense that it is oxidizable ∼560 mV (vs Ag/AgCl). This study is a first step in the utilization of black phosphorus in electrochemical applications.

[Communication]
Lu Wang, Zdenek Sofer, Martin Pumera
ChemElectroChem 2015, 2, No. 3, 324. Read article.

Structural Elucidation of the O‐Antigen Polysaccharide from Escherichia coli O181

[Full Paper]
Carolina Fontana, Andrej Weintraub, Göran Widmalm
ChemistryOpen 2015, 4, No. 1, 47. Read article.

A Highly Selective and Sensitive Turn‐On Fluorescent Chemosensor Based on Rhodamine 6G for Iron(III)

[Full Paper]
Zhi-Qiang Hu, Ying-Ying Gu, Wen-Zhou Hu, Lei-Li Sun, Jiang-Hua Zhu, Yi Jiang
ChemistryOpen 2014, 3, No. 6, 264. Read article.

Rechargeable Seawater Battery and Its Electrochemical Mechanism

Rechargeable Seawater Battery and Its Electrochemical Mechanism

Seawater cathode: The electrochemical mechanism of a novel rechargeable seawater battery system is explored. The seawater provides both anode (Na metal) and cathode (O2) materials for the proposed battery. Based on the discharge voltage (∼2.9 V) with participation of O2 and the charge voltage (∼4.1 V) with Cl2 evolution during the first cycle, a voltage efficiency of about 73 % is obtained.

[Communication]
Jae-Kwang Kim, Eungje Lee, Hyojin Kim, Christopher Johnson, Jaephil Cho, Youngsik Kim
ChemElectroChem 2015, 2, No. 3, 328. Read article.

Control of Spatial Organization of Electrospun Fibers in a Carbon Felt for Enhanced Bioelectrode Performance

Control of Spatial Organization of Electrospun Fibers in a Carbon Felt for Enhanced Bioelectrode Performance

How does it feel? Electrospun carbon felts were synthesized with either aligned or randomly distributed fibers (see picture). Resistivity measurements were realized to try to establish a normalized procedure for fibrous materials. Felts were modified with the enzyme laccase and tested towards the oxygen reduction reaction, which is typical for the cathode part of a biofuel cell.

[Full Paper]
Adriana Both Engel, Aziz Cherifi, Mikhael Bechelany, Sophie Tingry, David Cornu
ChemPlusChem 2015, 80, No. 3, 494. Read article.

Inhibition of Insulin‐Regulated Aminopeptidase (IRAP) by Arylsulfonamides

[Full Paper]
Sanjay R. Borhade, Ulrika Rosenström, Jonas Sävmarker, Thomas Lundbäck, Annika Jenmalm-Jensen, Kristmundur Sigmundsson, Hanna Axelsson, Fredrik Svensson, Vivek Konda, Christian Sköld, Mats Larhed, Mathias Hallberg
ChemistryOpen 2014, 3, No. 6, 256. Read article.

Efficient Regioselective Ring Opening of Activated Aziridine‐2‐Carboxylates with [18F]Fluoride

[Full Paper]
Christina Schjoeth-Eskesen, Paul Robert Hansen, Andreas Kjaer, Nic Gillings
ChemistryOpen 2015, 4, No. 1, 65. Read article.

The Generation Effect: Cavity Accessibility in Dense-Shell Polyphenylene Dendrimers

The Generation Effect: Cavity Accessibility in Dense-Shell Polyphenylene Dendrimers

It's all relative: The confined geometry of polyphenylene dendrimers leads to a clear generation effect because the size and access to the voids in these dendrimers is determined by their generation. Host–guest behavior to benzene, toluene, and xylenes (BTX) analytes was investigated by using quartz crystal microbalances.

[Communication]
Malte Brutschy, René Stangenberg, Cornelia Beer, Daniel Lubczyk, Martin Baumgarten, Klaus Müllen, Siegfried R. Waldvogel
ChemPlusChem 2015, 80, No. 1, 54. Read article.

Facile Synthesis of Hierarchical Magnesium Silicate Hollow Nanofibers Assembled by Nanosheets as an Efficient Adsorbent

Facile Synthesis of Hierarchical Magnesium Silicate Hollow Nanofibers Assembled by Nanosheets as an Efficient Adsorbent

Drop out! A synthetic route is described for the fabrication of magnesium silicate double-walled hollow nanofibers (MSHNFs; see picture), which exhibit excellent adsorption performance and can be easily separated from solution, from electrospun silica hollow nanofibers (SHNFs). The MSHNFs are demonstrated to be an efficient adsorbent for water purification.

[Full Paper]
Renxi Jin, Yang Yang, Yunfeng Li, Xiaodan Yu, Yan Xing, Shuyan Song, Zhan Shi
ChemPlusChem 2015, 80, No. 3, 544. Read article.