The Asian Chemical Editorial Society (ACES) is an organization of 13 major chemical societies in Asia and the Pacific. It was founded in 2005 as a conglomeration of chemical societies with the mutual aim of creating a modern publishing forum for research in Asia and coordinating future publishing activities.
The participating societies share a commitment to scientific excellence, to publishing ethics, and to the highest standards in publication, which are the basis for the success of Chemistry—An Asian Journal and its associated journals.
A sister journal of Angewandte Chemie and Chemistry—A European Journal
A sister journal of the European Journal of Organic Chemistry
For the publication of the AsianJOC, ACES is joined by the Korean Society of Organic Synthesis.
Supporting Organization: ChemPubSoc Europe
ACES supports the publication of the ChemPubSoc Europe journals Chemistry—A European Journal, the European Journal of Organic Chemistry, and ChemSusChem.
© Wiley-VCH 2012
A Good Year
Chem. Asian J. 2014 9, 4.
There's an App for That
Asian J. Org. Chem. 2014 3, 3.
A strong aversion to water: In an approach to water-resistant porous materials with a superhydrophobic surface without the use of alkylation or fluorination, a porous coordination polymer was synthesized with a low-symmetry nanoscale organic linker. The material exhibited superhydrophobicity (see picture) as a result of the surface corrugation created by the aromatic hydrocarbon and displayed selective uptake of organic molecules from water.
Koya Prabhakara Rao, Masakazu Higuchi, Kenji Sumida, Shuhei Furukawa, Jingui Duan, Susumu Kitagawa
Angew. Chem. Int. Ed. 2014, 53, No. 31, 8225. Read article.
The well-controlled synthesis of new graphene and graphene oxide derivatives as well as determination of the atomic structure are key challenges for synthetic chemists. Structure–property relationships must be exploited to use the full potential of graphene derivatives in upcoming applications. This Review focuses on concepts in the chemistry of graphene and graphene oxide with the aim of encouraging chemists to enhance the field of research.
Siegfried Eigler, Andreas Hirsch
Angew. Chem. Int. Ed. 2014, 53, No. 30, 7720. Read article.
O, I say! An N-formylmorpholine (NFM)-modulated one-pot glycosylation was used for the synthesis for construction of 1,2-cis α-glycosidic linkages in the synthesis of the pentasaccharide repeating unit of the O-antigen that is found in Escherichia coli O86.
Arun B. Ingle, Chin-Sheng Chao, Wei-Cheng Hung, Kwok-Kong Tony Mong
Asian J. Org. Chem. 2014, 3, No. 8, 870. Read article.
The incorporation of a pyrrole into a peptide backbone generates simple macrocycles that adopt a β-strand geometry. The attachment of a P1 amino aldehyde to these templates then gives rise to potent protease inhibitors (see example, top, which has Ki values of 440 pM and 920 pM against the cysteine cathepsins L and S, respectively). A crystal structure of a related derivative bound to chymotrypsin (see picture, bottom) confirms the design.
Krystle C. H. Chua, Markus Pietsch, Xiaozhou Zhang, Stephanie Hautmann, Hon Y. Chan, John B. Bruning, Michael Gütschow, Andrew D. Abell
Angew. Chem. Int. Ed. 2014, 53, No. 30, 7828. Read article.
Oxygen topochemistry: Nanoparticles of Bi3Ir, a hitherto uncharacterized intermetallic compound, reversibly intercalate oxygen from air at room temperature. In the resulting metallic suboxide, the intermetallic building units are preserved. The activation energy for oxide diffusion is one order of magnitude smaller than that in any known material. Bi3IrOx is the first metallic oxide ion conductor and also the first that operates at room temperature.
Martin Heise, Bertold Rasche, Anna Isaeva, Alexey I. Baranov, Michael Ruck, Konrad Schäfer, Rainer Pöttgen, Jens-Peter Eufinger, Jürgen Janek
Angew. Chem. Int. Ed. 2014, 53, No. 28, 7344. Read article.
Useful nitrogen-containing heterocycles can be rapidly synthesized from metal-catalyzed regioselective functionalization of enamides. This review discloses the progress made in the development of the direct C-H functionalization of enamides involving efficient and atom-economical routes (see scheme; EWG=electron-withdrawing group).
Nicolas Gigant, Laëtitia Chausset-Boissarie, Isabelle Gillaizeau
Chem. Eur. J. 2014, 20, No. 25, 7548. Read article.
Who's the DADA? The diaza-Diels–Alder (DADA) reaction was combined with palladium-catalyzed amination of bromoporphyrins to generate aminated porphyrins. The X-ray crystal structure of an anthracene-derived aminoporphyrin nickel(II) complex confirms the sequence.
Mean See Goh, Michael C. Pfrunder, John C. McMurtrie, Dennis P. Arnold
Asian J. Org. Chem. 2014, 3, No. 8, 856. Read article.
Getting your oligomers in a twist: Aminomethylenehelicene oligomers up to the heptamer were synthesized by reductive amination reactions, and the oligomers containing more than three helicenes formed double helices. The oligomers unfold and fold in response to heating and cooling, accompanied by a two-sided thermal hysteresis. Structural changes within the oligomers are also reversible by treatment with acid or base.
Masanori Shigeno, Masahiko Sato, Yo Kushida, Masahiko Yamaguchi
Asian J. Org. Chem. 2014, 3, No. 7, 797. Read article.
Dual functions: The incorporation of two different functional groups, a tetracyanoanthra-para-quinodimethane (TCAQ) unit and an imidazolium-based ionic liquid, on single-wall carbon nanotubes (SWCNTs; see the picture) creates a potential electroactive material with tunable hydrophilic/hydrophobic polarity by simple ion exchange. The functional group position was interchanged and further studied to evaluate its influence.
Laura Rodríguez-Pérez, Raúl García, María Angeles Herranz, Nazario Martín
Chem. Eur. J. 2014, 20, No. 24, 7278. Read article.
New Sc3+ carrier delivers: Complexes of trivalent scandium with 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) and diethylenetriamine-N,N,N',N'',N''-pentaacetic acid (DTPA) were investigated in solution and in the solid state. Potentiometry and multinuclear NMR spectrometry revealed relatively fast complexation of Sc3+ with DOTA, as well as very high stability constants and high kinetic inertness for the complex. The data confirmed that DOTA-like ligands are very suitable for the development of scandium-based radiopharmaceuticals (see figure).
Miroslav Pniok, Vojtech Kubíček, Jana Havlíčková, Jan Kotek, Andrea Sabatie-Gogová, Jan Plutnar, Sandrine Huclier-Markai, Petr Hermann
Chem. Eur. J. 2014, 20, No. 26, 7944. Read article.
R.C.M.: The structure and biological activity of five-membered carbocyclic nucleosides have motivated chemists over the last several decades to synthesize these compounds. Ring-closing metathesis (RCM) has evolved as an effective tool for making these deceptively simple molecules. The impact of RCM culminated in several strategies for the synthesis of nucleoside analogues from carbohydrates or chiral auxiliaries. Bn=benzyl; TBDPS=tert-butyldiphenylsilyl; Tr=trityl.
Varughese A. Mulamoottil, Akshata Nayak, Lak Shin Jeong
Asian J. Org. Chem. 2014, 3, No. 7, 748. Read article.
Dual-site click labeling: A ligand-assisted CuAAC reaction, pyrrolysine-based genetic code expansion strategy, and the PRIME labeling technique were integrated for dual-site click labeling of EGFR at the surface of mammalian cells. This strategy enabled simultaneous installation of a FRET donor–acceptor pair onto the extracellular domains of EGFR, thereby allowing cis-membrane FRET imaging of receptor dynamics.
Yi Yang, Shixian Lin, Wei Lin, Peng R. Chen
ChemBioChem 2014, 15, No. 12, 1738. Read article.
Bond after bond: A series of polychalcogenotrimethylsilane complexes Ar(CH2ESiMe3)n (Ar=aryl; E=S, Se; n=2, 3, and 4) have been prepared that incorporate a large number of reactive -ESiMe3 moieties onto an organic molecular framework (see figure). They are shown to be convenient reagents for the preparation of the polyferrocenylseleno- and thioesters from ferrocenoyl chloride.
Mahmood Azizpoor Fard, Bahareh Khalili Najafabadi, Mahdi Hesari, Mark S. Workentin, John F. Corrigan
Chem. Eur. J. 2014, 20, No. 23, 7037. Read article.
The control of the helix handedness of water-soluble quinoline-based oligoamide foldamers has been investigated by the installation of chiral end groups at either the N or C terminus. This has respectively afforded either quantitative induction of handedness or the ability to separate kinetically locked P and M helices as diastereoisomers.
Simon J. Dawson, Adám Mészáros, Lilla Pethő, Cinzia Colombo, Márton Csékei, András Kotschy, Ivan Huc
Eur. J. Org. Chem. 2014, No. 20, 4265. Read article.
The life of π: Pt-based quinoline and benzothiazole complexes were synthesized with an aim to design drugs with higher affinity for π–π stacking and electrostatic interactions with targeted biomolecules. Fluorescence spectroscopy and molecular modeling led to candidate complexes with significant cytotoxicity toward various tumor cell lines.
Erin S. F. Ma, A. Gerard Daniel, Nicholas P. Farrell
ChemMedChem 2014, 9, No. 6, 1155. Read article.
Two different paths: Phosphonium azolide ionic liquids of interest for CO2 capture applications react with CO2 both through the normal anion channel and, at elevated temperatures, through a previously unrecognized cation channel. The cation channel involves a phosphonium ylide intermediate that is formed due to cation/anion interactions. This channel is suppressed with less-acidic ammonium cations.
Thomas R. Gohndrone, Tae Bum Lee, M. Aruni DeSilva, Mauricio Quiroz-Guzman, William F. Schneider, Joan F. Brennecke
ChemSusChem 2014, 7, No. 7, 1970. Read article.
Brains not Brønsted: Sulfonyl-containing ammonium-based Brønsted acid ionic liquids (ILs) are prepared and used as liquid heterogeneous catalysts for organic reactions under solvent-free conditions. The sulfonyl group endowed these ILs with unique macroscopic phase heterogeneity in the reaction system, ensuring outstanding catalytic activities of the ILs. These catalytic systems are applicable in a wide range of acid-catalyzed reactions.
Amir Taheri, Xiaojuan Pan, Changhui Liu, Yanlong Gu
ChemSusChem 2014, 7, No. 8, 2094. Read article.
More red wine, please: Resveratrol, a signaling protein modulator, can exert off-target effects involving peroxisome proliferator-activated receptors (PPARs). Results from chromatographic and isothermal titration calorimetry experiments indicate that resveratrol and its metabolites bind PPARγ directly, but only resveratrol interacts with PPARα, thus suggesting a new pattern of receptor–ligand recognition.
Enrica Calleri, Giorgio Pochetti, Katina S. S. Dossou, Antonio Laghezza, Roberta Montanari, Davide Capelli, Ellen Prada, Fulvio Loiodice, Gabriella Massolini, Michel Bernier, Ruin Moaddel
ChemBioChem 2014, 15, No. 8, 1154. Read article.
Trypsin in reverse: Trypsiligase (trypsin K60E/N143H/E151H/D189K) was used for highly selective PEGylation of the anti-Her2 Fab fragment under native conditions. The approach resulted in a fully functional antibody fragment with good product yield.
Sandra Liebscher, Petra Kornberger, Gerhard Fink, Eva-Maria Trost-Gross, Eva Höss, Arne Skerra, Frank Bordusa
ChemBioChem 2014, 15, No. 8, 1096. Read article.
A monofluoro-substituted cyclobutane-derived amino acid was designed and synthesized as a 19F label for studying membrane-bound peptides by solid-state 19F NMR spectroscopy. This amino acid can be safely used to replace aromatic proteinogenic amino acids (Phe, Tyr) within α-helices and β-turns. This was demonstrated experimentally in the cyclic gramicidin S, as well as by molecular modeling.
Anton N. Tkachenko, Pavel K. Mykhailiuk, Dmytro S. Radchenko, Oleg Babii, Sergii Afonin, Anne S. Ulrich, Igor V. Komarov
Eur. J. Org. Chem. 2014, No. 17, 3584. Read article.
The enantiospecific synthesis and biological activities of a nuphar alkaloid have been described. Reliable and scalable chemistry was used to synthesize the alkaloid in nine steps, and an affinity to three central nervous system (CNS) receptors, including the oxytocin receptor, was found.
Hajime Seki, Gunda I. Georg
Eur. J. Org. Chem. 2014, No. 18, 3777. Read article.
Creating new basic sites: Through activation treatments in alkaline media, basic sites with high activity, stability, and selectivity are generated in high-silica FAU, BEA, and MFI zeolites, which enable the efficient deoxygenation of pyrolysis oil by condensation reactions. Intermediate bio-oil upgrading is key for the sustainable and profitable production of advanced biofuels.
Tobias C. Keller, Elodie G. Rodrigues, Javier Pérez-Ramírez
ChemSusChem 2014, 7, No. 6, 1729. Read article.
Pd ORR Au: Palladium nanotubes (PdNTs) and gold nanotubes (AuNTs) are studied as oxygen reduction reaction (ORR) and alcohol oxidation reaction catalysts in base. PdNTs and AuNTs produce ORR area activities that are 2.9 and 2.3 times greater than those produced by Pd/C and Au/C, respectively. The PdNTs further show improved methanol, ethanol, and ethylene glycol oxidation activity in comparison to nanoparticle catalysts.
Shaun M. Alia, Kathlynne Duong, Toby Liu, Kurt Jensen, Yushan Yan
ChemSusChem 2014, 7, No. 6, 1739. Read article.
Metal with mettle: Catalytic metallodrugs are a new compound class with potential for high therapeutic activity and low toxicity. The Cu-GGHYrFK-amide complex was reported earlier to catalytically inactivate stem loop IIb of the HCV internal ribosomal entry site RNA, and to show significant antiviral activity in a cellular HCV replicon assay. Herein we describe our studies focused on understanding the cleavage mechanism and the relationship of catalyst configuration to structural recognition and site-selective cleavage of the structured RNA motif.
Seth S. Bradford, Martin James Ross, Insiya Fidai, James A. Cowan
ChemMedChem 2014, 9, No. 6, 1275. Read article.
A new method for construction of the pyrroloindoline framework by way of arenediazonium-triggered cyclization of tryptamines allows for direct and efficient access to a synthetically important structural motif. The reaction is the first example of diazonium-induced 1,2-diamination.
David E. Stephens, Oleg V. Larionov
Eur. J. Org. Chem. 2014, No. 17, 3662. Read article.
Photo opportunity: We report the genetic encoding of a furan-based, photo-crosslinking amino acid in human cells by a mutant pyrrolysyl-tRNA synthetase (PylRS) with broad polyspecificity. Crystal structures of this enzyme reveal the mode of furan amino acid recognition and the basis of polyspecificity, thus providing a promising starting point for engineering PylRS mutants with increased substrate scope.
Moritz J. Schmidt, Annemarie Weber, Moritz Pott, Wolfram Welte, Daniel Summerer
ChemBioChem 2014, 15, No. 12, 1755. Read article.
Just tin time! SnS2 nanoplatelets were incorporated with graphene by using a facile hydrothermal method. Graphene nanosheets act as a heterogeneous dispersing agent to prevent the aggregation of SnS2 nanoplatelets and provide electrically conductive networks, which lead to an improved electrochemical performance for sodium-ion storage (see figure).
Xiuqiang Xie, Dawei Su, Shuangqiang Chen, Jinqiang Zhang, Shixue Dou, Guoxiu Wang
Chem. Asian J. 2014, 9, No. 6, 1611. Read article.
More NHC-organocatalysis: N-Heterocyclic carbene-catalyzed reactions of indolin-3-ones with 2-bromoenals opened an asymmetric access to 3,4-dihydropyrano[3,2-b]indol-2(5 H)-ones in good yields and with good to excellent enantioselectivities. This protocol tolerates a broad substrate scope. In addition, a possible mechanism for the annulation reaction is presented.
Qijian Ni, Xiaoxiao Song, Gerhard Raabe, Dieter Enders
Chem. Asian J. 2014, 9, No. 6, 1535. Read article.
Polyoxometalates, like small pieces of metal oxide, can be dissolved or fixed on a surface to perform homogeneous or heterogeneous catalysis, respectively. Here we exploit the alkaline nature of polyoxoniobates to neutralize nerve agents in both solution and the solid state. Solution studies correlate reaction efficacy to the association of the dissolved polyoxoniobate with its counterions.
Mark K. Kinnan, William R. Creasy, Lauren B. Fullmer, Heidi L. Schreuder-Gibson, May Nyman
Eur. J. Inorg. Chem. 2014, No. 14, 2361. Read article.
Pièce de résistance! Multidrug resistance (MDR) is the main obstacle toward effective anticancer therapy. Herein we report the discovery of two small-molecule 14-3-3 protein–protein interaction inhibitors that promote the translocation of c-Abl and FOXO pro-apoptotic factors into the nucleus and sensitize MDR cancer cells to doxorubicin and the pan-Akt inhibitor GSK690693.
Mattia Mori, Giulia Vignaroli, Ylenia Cau, Jelena Dinić, Richard Hill, Matteo Rossi, David Colecchia, Milica Pešić, Wolfgang Link, Mario Chiariello, Christian Ottmann, Maurizio Botta
ChemMedChem 2014, 9, No. 5, 973. Read article.
Keeping on the ultralow: Quantitative information about the journey of sulfur molecules inside an operating ultralow sulfur diesel reactor is provided. This information coupled with other new insights obtained under realistic industrial conditions is expected to significantly increase the effectiveness of future studies aimed at increasing the efficiency of the ultralow sulfur diesel process. ppmw=parts per million by weight
Tushar V. Choudhary, Kening Gong, Phillipp Ellison, Ayyappan Subbiah
ChemCatChem 2014, 6, No. 6, 1782. Read article.
Great things in small packages: Large-area α-MnO2 nanoflower arrays on flexible substrates are synthesized through a facial template-free electrochemical deposition process. These nanoflower arrays produce an enhanced electrochemical performance in the form of a high specific capacitance with remarkable rate capability and excellent cycling stability.
Wenyao Li, Kaibing Xu, Bo Li, Jianqing Sun, Feiran Jiang, Zhishui Yu, Rujia Zou, Zhigang Chen, Junqing Hu
ChemElectroChem 2014, 1, No. 6, 1003. Read article.
Bent on stability: The nematic liquid-crystal phases formed by bent-core molecules have remarkable properties. This Minireview reports recent progress in stabilizing the nematic phase at accessible temperatures, concentrating on oxadiazole-based materials. It also describes recent measurements of their physical properties, including optical, dielectric, elastic, and flexoelectric coefficients, and electric field effects (see graphic).
Helen F. Gleeson, Sarabjot Kaur, Verena Görtz, Abdel Belaissaoui, Stephen Cowling, John W. Goodby
ChemPhysChem 2014, 15, No. 7, 1251. Read article.
Separation is never easy: With the goal of achieving effective ethylene/ethane separation, we evaluated the gas sorption properties of four flexible pillared-layer-type porous coordination polymers (PCPs) with double interpenetration. Among these compounds, a PCP containing the narrowest pores exhibits ethylene-selective sorption property at ambient temperature and pressure, as examined by breakthrough experiments with ethylene/ethane gas mixtures.
Keisuke Kishida, Satoshi Horike, Yoshihiro Watanabe, Mina Tahara, Yasutaka Inubushi, Susumu Kitagawa
Chem. Asian J. 2014, 9, No. 6, 1643. Read article.
Study history, study history: Visible-light-driven Co3O4 spinel water oxidation catalysts (WOCs) were hydrothermally prepared and investigated with respect to the influence of preparative history on the catalytic activity. We present a counterintuitive design trend: crystallinity and valence states are more important for WOC performance than surface area. New “top down” and “bottom up” strategies for Co3O4 WOC optimization are proposed.
Hongfei Liu, Greta R. Patzke
Chem. Asian J. 2014, 9, No. 8, 2249. Read article.
Special effects in 2D: The temperature-dependent Raman spectra of single- and few-layer MoSe2 and WSe2 in the 77–700 K range are reported. Linear variation is observed in the peak positions and widths of the bands arising from contributions of anharmonicity and thermal expansion.
Dattatray J. Late, Sharmila N. Shirodkar, Umesh V. Waghmare, Vinayak P. Dravid, C. N. R. Rao
ChemPhysChem 2014, 15, No. 8, 1592. Read article.
De novo designed α-helical peptides have been used to design structural and functional copper sites in minimum protein scaffolds. The design of structural copper Type 1, Type 2, Type A, and Cu–SCys centers in α-helical constructs is described. Catalytic copper Type 2 centers are also presented, along with their functional features.
Eur. J. Inorg. Chem. 2014, No. 13, 2177. Read article.
Control freak: The final product of important multistep electrode reactions, such as the electro-reduction of oxygen, depends on the extent of a surface-catalysed reaction and, therefore, on the nature and coverage of the nanoparticles employed for the electrode modification.
Eduardo Laborda, Christopher C. M. Neumann, Ying Wang, Kristopher R. Ward, Angela Molina, Richard G. Compton
ChemElectroChem 2014, 1, No. 5, 909. Read article.
Sheath shielding: It is shown that if significant adsorption occurs on the sheath used to insulate a microdisc electrode, then it can have a high impact on the measured current–time data because of a considerable shielding effect. Chronoamperograms are simulated as a function of the sheath-to-disc electrode radius ratio and the rate constant for adsorption onto the sheath.
Shaltiel Eloul, Richard G. Compton
ChemElectroChem 2014, 1, No. 5, 917. Read article.
Gold renaissance! Gold(I) N-heterocyclic carbene complexes with phosphane ligands effectively inhibit the the seleno-enzyme thioredoxin reductase (TrxR) and the zinc-finger enzyme poly(ADP-ribose) polymerase 1 (PARP-1) and trigger potent cytotoxicity in cancer cells.
Riccardo Rubbiani, Luca Salassa, Andreia de Almeida, Angela Casini, Ingo Ott
ChemMedChem 2014, 9, No. 6, 1205. Read article.
Film star: A new method for drying cholesteric liquid-crystalline cellulose nanocrystal suspensions into solid films avoids phase coexistence and, with an applied circular shear flow, yields unprecedented structural control. The commonly observed mosaic-like structure, with randomly varying orientation of the cholesteric helix axis, is replaced by a macroscopically uniform film with improved optical properties (see figure).
Ji Hyun Park, JungHyun Noh, Christina Schütz, German Salazar-Alvarez, Giusy Scalia, Lennart Bergström, Jan P. F. Lagerwall
ChemPhysChem 2014, 15, No. 7, 1477. Read article.
It's all in the prep: Novel sample preparation for X-ray nanotomography by using focused-ion-beam (FIB) and micromanipulation ensures high-quality data. The proposed procedure resolves the issues that cause the view of the sample base to be blocked after FIB milling and during the lift-out process. This method enables the broad application of X-ray nanotomography in microstructure studies.
Yu-chen Karen Chen-Wiegart, Fernando E. Camino, Jun Wang
ChemPhysChem 2014, 15, No. 8, 1587. Read article.
Mini techniques, bigger picture: A combination of advanced characterization techniques, synchrotron X-ray micro- and nanotomography, micro-X-ray fluorescence, and micro-XRD, are used to characterize a commercial spent equilibrium fluid catalytic cracking catalyst at both the ensemble and individual particle level.
Simon R. Bare, Meghan E. Charochak, Shelly D. Kelly, Barry Lai, Jun Wang, Yu-chen Karen Chen-Wiegart
ChemCatChem 2014, 6, No. 5, 1427. Read article.
Back to the FTIR: The most efficient organocatalysts have been identified for the reaction of alcohols with isocyanates in supercritical CO2 in a step towards a green process for polyurethane synthesis. The order of activity of the catalysts in supercritical CO2 does not always follow that observed in conventional media.
Christopher A. Smith, Henri Cramail, Thierry Tassaing
ChemCatChem 2014, 6, No. 5, 1380. Read article.
A solution-phase self-assembly and solid-phase carbonization route for the synthesis of uniform hollow carbon microspheres embedded with Li4Ti5O12 nanoparticles has been developed. The microsized spherical Li4Ti5O12@C hollow composites have conductive carbon shells, which endow them with high specific capacity, rate capability, electrode density, and cycle stability.
Jun Liu, Wei Liu, Shaomin Ji, Yanling Wan, Huaqi Yin, Yichun Zhou
Eur. J. Inorg. Chem. 2014, No. 12, 2073. Read article.
Kinetic evidence of the tautomerism of thiourea dioxide in aqueous acidic solutions is reported. The reactivity of the two tautomeric forms towards ClO2 significantly differs in rate and also in mechanistic aspects. Whereas aminoiminomethanesulfinic acid reacts with ClO2 in a second-order process, the reaction of its tautomeric form, thiourea dioxide, with ClO2 displays autocatalysis.
György Csekő, Ying Hu, Yanan Song, Tímea R. Kégl, Qingyu Gao, Sergei V. Makarov, Attila K. Horváth
Eur. J. Inorg. Chem. 2014, No. 11, 1875. Read article.
Follow the organoborate road: Competition Suzuki–Miyaura reactions between two boronic acids with different pKa values reveal the link between acid–base chemistry and the reaction catalytic cycle. The results reveal that the borate path is the preferred route for transmetalation and thus confirm the role of the base in the reaction mechanism.
Carlos F. R. A. C. Lima, Ana S. M. C. Rodrigues, Vera L. M. Silva, Artur M. S. Silva, Luís M. N. B. F. Santos
ChemCatChem 2014, 6, No. 5, 1291. Read article.
Not only a girl's best friend: Boron-doped diamond is important as an electrode material. Oxygen-terminated diamonds and the kinetics of OH generation in alkaline solutions on this type of surface are studied theoretically; this allows detailed structure and energetics characterization of the systems, as well as an understanding of the reaction dynamics that proceed in an outer-sphere mode.
Paola M. Quaino, Wolfgang Schmickler
ChemElectroChem 2014, 1, No. 5, 933. Read article.
Paving the way: The successful preparation of biocompatible hybrids by integrating graphene oxide with amphiphilic pillararenes for in vitro Raman and fluorescence dual-mode bioimaging has been carried out (see scheme), thereby paving the way for utilizing these materials in combined cancer diagnostics.
Huacheng Zhang, Xing Ma, Kim Truc Nguyen, Yongfei Zeng, Shuhui Tai, Yanli Zhao
ChemPlusChem 2014, 79, No. 3, 462. Read article.
Soaking it up: RGO/Co3O4 nanohybrid particles have been successfully fabricated by using an in situ growth approach under mild wet-chemical conditions (see scheme). From this, RGO/Co3O4/poly(vinylidene fluoride) composites with excellent absorption properties were obtained and characterized.
Guang-Sheng Wang, Yun Wu, Yun-Zhao Wei, Xiao-Juan Zhang, Yong Li, Li-Dong Li, Bo Wen, Peng-Gang Yin, Lin Guo, Mao-Sheng Cao
ChemPlusChem 2014, 79, No. 3, 375. Read article.
Grass roots: Template-free electrochemical polymerization in phosphate buffer solution has been used to obtain grasslike polypyrrole (PPy) nanowires of low density on titanium (see figure). By introducing a prenucleation film on the titanium, conducting PPy nanotube arrays (CPNAs) of large area were fabricated. The architectures of the CPNAs can be finely tuned between cones and cylinders by changing the electrochemical parameters.
Jingwen Liao, Chengyun Ning, Guoxin Tan, Guoxin Ni, Haobo Pan
ChemPlusChem 2014, 79, No. 4, 524. Read article.
Supporting role: Peptide nanofibers have been used as a template for the in situ generation of palladium nanoparticles. Peptide-nanofiber-supported palladium nanoparticles show efficient catalytic activity towards deprotection of N-terminus amino acids and peptides under mild conditions (see figure).
Indrajit Maity, Manoj K. Manna, Dnyaneshwar B. Rasale, Apurba K. Das
ChemPlusChem 2014, 79, No. 3, 413. Read article.
Non-hinge binding: A novel organometallic protein kinase inhibitor scaffold based on a cyclometalated 1,8-phenanthrolin-7(8 H)-one ligand is reported, which binds to the ATP binding site of the protein kinase Pim1 in an unexpected, unusual non-ATP-mimetic fashion without mimicking the hydrogen-bonding interaction of the adenine nucleobase of ATP.
Kathrin Wähler, Katja Kräling, Holger Steuber, Eric Meggers
ChemistryOpen 2013, 2, No. 5-6, 180. Read article.
Trapped within: We report single-crystal characterization of polymorphs of the ammonium carbamate self-derivative salt of prolinamide, and the first crystal structure of prolinamide and of derived products. This study emphasizes the reactivity of carbonated amines in the solid state and opens perspectives for a systematic study of (solid-state) reactions involving these trapped reactive species.
Anaëlle Tilborg, Steve Lanners, Bernadette Norberg, Johan Wouters
ChemistryOpen 2013, 2, No. 5-6, 194. Read article.
Simple and effective: A facile procedure for monitoring chemical reactions and characterizing compounds dissolved in ionic liquids is described using the MS/MS technique. Separation of species of interest was carried out using internal electronic gate available in electrospray mass spectrometers, instead of chromatography and extraction. The separation was carried out as a fast (milliseconds) and sustainable (no extra solvents) procedure.
Levon L. Khemchyan, Elena A. Khokhlova, Marina M. Seitkalieva, Valentine P. Ananikov
ChemistryOpen 2013, 2, No. 5-6, 208. Read article.
Water purification with β-Bi2O3: A straightforward synthetic procedure for the synthesis of β-Bi2O3 nanoparticles that offers the potential for gram-scale production is presented. The β-Bi2O3 nanoparticles show high photocatalytic activity and stability in the degradation of typical organic water pollutants under visible light irradiation. These nanoparticles might be promising materials for use in novel water purification systems.
Maik Schlesinger, Marcus Weber, Steffen Schulze, Michael Hietschold, Michael Mehring
ChemistryOpen 2013, 2, No. 4, 146. Read article.