Mission Statement

The Asian Chemical Editorial Society (ACES) is an organization of 13 major chemical societies in Asia and the Pacific. It was founded in 2005 as a conglomeration of chemical societies with the mutual aim of creating a modern publishing forum for research in Asia and coordinating future publishing activities.

The participating societies share a commitment to scientific excellence, to publishing ethics, and to the highest standards in publication, which are the basis for the success of Chemistry—An Asian Journal and its associated journals.

Publications

Chemistry—An Asian Journal

A sister journal of Angewandte Chemie and Chemistry—A European Journal

Supporting Organizations: ChemPubSoc Europe, Gesellschaft Deutscher Chemiker (German Chemical Society, GDCh), Federation of Asian Chemical Societies (FACS).

Asian Journal of Organic Chemistry

A sister journal of the European Journal of Organic Chemistry

For the publication of the AsianJOC, ACES is joined by the Korean Society of Organic Synthesis.

Supporting Organization: ChemPubSoc Europe

ACES supports the publication of the ChemPubSoc Europe journals Chemistry—A European Journal, the European Journal of Organic Chemistry, and ChemSusChem.

© Wiley-VCH 2012

Journals

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Chem Asian J

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Asian J Org Chem

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AsianJOC for iPad

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ChemNanoMat

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Angew Chem

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Chem Eur J

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Eur J Org Chem

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ChemSusChem

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Chem Rec

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News

Editorials: New Developments

Chemistry - An Asian Journal Theresa Kueckmann
A Reason to Celebrate!
Chem. Asian J. 2015 10, 4.

Asian Journal of Organic ChemistryRichard Threlfall
Something Old, Something New, Something Borrowed, Something Blue
Asian J. Org. Chem. 2015 4, 4.

Asian Journal of Organic ChemistryTheresa Kueckmann, Claire Cobley
ChemNanoMat—A New Journal for Small Science with a Big Impact
ChemNanoMat 2015 DOI: 10.1002/cnma.201500007.

 

Research of the DayEditors' Choice: Spotlights

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Enantioselective Catalysis of Photochemical Reactions

Enantioselective Catalysis of Photochemical Reactions

All good things come in threes: With catalysis, light, and chirality, three of the most important scientific phenomena merge in the field of the enantioselective catalysis of photochemical reactions. This Review introduces the main concepts and provides an overview of the key findings in this area.

[Review]
Richard Brimioulle, Dominik Lenhart, Mark M. Maturi, Thorsten Bach
Angew. Chem. Int. Ed. 2015, 54, No. 13, 3872. Read article.

Catalytic Upgrading of Biomass-Derived Methyl Ketones to Liquid Transportation Fuel Precursors by an Organocatalytic Approach

Catalytic Upgrading of Biomass-Derived Methyl Ketones to Liquid Transportation Fuel Precursors by an Organocatalytic Approach

Dimerize it: A highly efficient, water-tolerant, solid-base organocatalyst for selective dimerization of biomass-derived methyl ketones was developed by tethering amines on a Brønsted acidic silica–alumina support. C4–C15 methyl ketones can be catalytically upgraded to the dimer products with high selectivity. DFT analysis and experimental data suggest that C-C bond formation is the rate-determining step.

[Communication]
Shylesh Sankaranarayanapillai, Sanil Sreekumar, Joseph Gomes, Adam Grippo, George E. Arab, Martin Head-Gordon, F. Dean Toste, Alexis T. Bell
Angew. Chem. Int. Ed. 2015, 54, No. 15, 4673. Read article.

Synthesis, Photophysics, and Electronic Structures of Benzene-Linked Bispyrimidine Compounds

Synthesis, Photophysics, and Electronic Structures of Benzene-Linked Bispyrimidine Compounds

Two or tree? Seven multidipole and multibranched benzene-linked bispyrimidine derivatives containing a two-layer binary tree structure have been designed, synthesized, and characterized. Their photophysics and transient difference absorption properties as well as DFT calculations suggest these compounds may be used as optical limiting material.

[Full Paper]
Guangliang Song, Rui Liu, Guangke He, Shidong Yuan, Hongjun Zhu
Asian J. Org. Chem. 2015, 4, No. 4, 346. Read article.

Photonic Patterns Printed in Chiral Nematic Mesoporous Resins

Photonic Patterns Printed in Chiral Nematic Mesoporous Resins

Printing photonic patterns made easy: Using chemical “inks”, latent photonic patterns were written onto chiral nematic mesoporous-resin films. The patterns are invisible in the dry films, but emerge upon swelling. Inkjet printing of the resin films afforded high-resolution photonic patterns that can be revealed upon swelling and erased by drying, making them suitable for anti-counterfeiting applications.

[Communication]
Mostofa K. Khan, Anas Bsoul, Konrad Walus, Wadood Y. Hamad, Mark J. MacLachlan
Angew. Chem. Int. Ed. 2015, 54, No. 14, 4304. Read article.

“We Create Chemistry for a Sustainable Future”: Chemistry Creates Sustainable Solutions for a Growing World Population

“We Create Chemistry for a Sustainable Future”: Chemistry Creates Sustainable Solutions for a Growing World Population

On April 6, 1865, Friedrich Engelhorn founded the company “Badische Anilin- & Sodafabrik” in Mannheim, Germany. This Essay, commemorating the 150th anniversary of BASF, introduces several outstanding examples of innovation from the history of BASF and highlights how chemical and technical competencies developed in the past still play an essential role in current projects.

[Essay]
Andreas Kreimeyer, Peter Eckes, Christian Fischer, Harald Lauke, Peter Schuhmacher
Angew. Chem. Int. Ed. 2015, 54, No. 11, 3178. Read article.

Supramolecular Architectures Incorporating Hydrogen-Bonding Barbiturate Receptors

Supramolecular Architectures Incorporating Hydrogen-Bonding Barbiturate Receptors

Good hosts: An overview of Hamilton-type bis(amidopyridine) receptor motifs, which offer strong and selective binding in non-competitive media for barbiturates and cyanurates, leading to a wide range of supramolecular assemblies, is presented. A particular emphasis is placed on photoaddressable systems.

[Focus Review]
Arnaud Tron, Mathias Rocher, Peter J. Thornton, James H. R. Tucker, Nathan D. McClenaghan
Asian J. Org. Chem. 2015, 4, No. 3, 192. Read article.

Palladium-Catalyzed Oxidative C-C Bond Cleavage of α-Hydroxyketones: Application to C-H Acylation of Azoarenes and Synthesis of a Liver(X) Receptor Agonist

Palladium-Catalyzed Oxidative C-C Bond Cleavage of α-Hydroxyketones: Application to C-H Acylation of Azoarenes and Synthesis of a Liver(X) Receptor Agonist

Soul acyl-um: Palladium-catalyzed oxidative C-C cleavage of α-hydroxyketones and 2-aryl acetophenones in the presence of tert-butyl hydrogen peroxide (TBHP) and subsequent C-H acylation of azoarenes with the generated acyl moiety provides easy access to acyl azoarenes.

[Full Paper]
Biju Majhi, Sabir Ahammed, Debasish Kundu, Brindaban C. Ranu
Asian J. Org. Chem. 2015, 4, No. 2, 154. Read article.

Triarylamine-Free Pyrenoimidazole-Containing Organic Dyes with Different π-Linkers for Dye-Sensitized Solar Cells

Triarylamine-Free Pyrenoimidazole-Containing Organic Dyes with Different π-Linkers for Dye-Sensitized Solar Cells

A piece of the π: A series of amine-free bipolar dyes featuring a pyrenoimidazole donor, a cyanoacrylic acid acceptor, and different π-linkers is reported. The dyes were used as sensitizers in dye-sensitized solar cells and their efficiencies are moderate.

[Full Paper]
Dhirendra Kumar, K. R. Justin Thomas, Chuan-Pei Lee, Kuo-Chuan Ho
Asian J. Org. Chem. 2015, 4, No. 2, 164. Read article.

How a [CoIV${^{\underline{.....}}}$O]2+ Fragment Oxidizes Water: Involvement of a Biradicaloid [CoII–(·O·)]2+ Species in Forming the O-O Bond

How a [CoIV${^{\underline{.....}}}$O]2+ Fragment Oxidizes Water: Involvement of a Biradicaloid [CoII–(·O·)]2+ Species in Forming the O-O Bond

Quantum leap: Quantum chemical models based on density functional theory are used to study the mechanism of water oxidation performed by a recently discovered cobalt complex (Py5=2,6-(bis(bis-2-pyridyl)-methoxymethane)pyridine). It was shown that the most catalytically active species is the intermediate-spin quartet complex that is almost isoenergetic with the doublet state.

[Full Paper]
Douglas W. Crandell, Soumya Ghosh, Curtis P. Berlinguette, Mu-Hyun Baik
ChemSusChem 2015, 8, No. 5, 844. Read article.

Synthesis of 3'-Fluoro-tRNA Analogues for Exploring Non-ribosomal Peptide Synthesis in Bacteria

Synthesis of 3'-Fluoro-tRNA Analogues for Exploring Non-ribosomal Peptide Synthesis in Bacteria

Fluorinated aminoacyl-tRNA analogues: Semisynthetic routes to fluoro analogues of tRNAAla and Ala-tRNAAla have been developed. These molecules are non-isomerisable analogues of the substrates of alanyl-tRNA synthetases and FemX transferases and should provide new insight into substrate recognition by these enzymes.

[Full Paper]
Laura Iannazzo, Guillaume Laisné, Matthieu Fonvielle, Emmanuelle Braud, Jean-Philippe Herbeuval, Michel Arthur, Mélanie Etheve-Quelquejeu
ChemBioChem 2015, 16, No. 3, 477. Read article.

Light-Triggered Capture and Release of DNA and Proteins by Host–Guest Binding and Electrostatic Interaction

Light-Triggered Capture and Release of DNA and Proteins by Host–Guest Binding and Electrostatic Interaction

Cyclodextrin vesicles bind charged biomolecules, such as DNA or proteins, in the presence of light-responsive charged guest molecules. The complexes can be disassembled under UV-light irradiation based on trans/cis isomerization of the azobenzene guests (see figure).

[Full Paper]
Johanna Moratz, Avik Samanta, Jens Voskuhl, Siva Krishna Mohan Nalluri, Bart Jan Ravoo
Chem. Eur. J. 2015, 21, No. 8, 3271. Read article.

From Amino Acids to Fluorine-Containing Carbohydrates: De Novo Synthesis of 2-Amino-4-Fluoroxylose and -lyxose

From Amino Acids to Fluorine-Containing Carbohydrates: De Novo Synthesis of 2-Amino-4-Fluoroxylose and -lyxose

Fluorinated derivatives of amino-xylose and -lyxose have been prepared by aldolization of D- and L-cysteine-derived aldehydes and a fluoroacetyl ephedrine oxazolidinone auxiliary. Photochemical Pummerer-type rearrangement followed by acidic cleavage of the protecting groups subsequently furnished the title compounds in overall yields of 47–48 % over four steps.

[Full Paper]
Christopher Albler, Walther Schmid
Eur. J. Org. Chem. 2015, No. 6, 1314. Read article.

Linked Supramolecular Building Blocks for Enhanced Cluster Formation

Linked Supramolecular Building Blocks for Enhanced Cluster Formation

The butterfly effect: Calix[4]arenes are versatile structural supports for polymetallic clusters possessing fascinating magnetic properties. Bis-calix[4]arene is shown to offer enhanced control over the assembly of such species, and a rational approach towards the targeted synthesis of complex and challenging structures.

[Full Paper]
Ross McLellan, Maria A. Palacios, Christine M. Beavers, Simon J. Teat, Stergios Piligkos, Euan K. Brechin, Scott J. Dalgarno
Chem. Eur. J. 2015, 21, No. 7, 2804. Read article.

A Highly Resilient Mesoporous SiOx Lithium Storage Material Engineered by Oil–Water Templating

A Highly Resilient Mesoporous SiOx Lithium Storage Material Engineered by Oil–Water Templating

All's well with oil: Carbon-coated porous SiOx is synthesized by a facile and scalable approach, that is, a sol–gel reaction of hydrogen silsesquioxane together using oil–water templating. A hydrophobic oil is used as both, a pore former inside the SiOx matrix and a precursor for carbon encapsulation on the surface of SiOx. The resulting anode material exhibits a high reversible capacity and outstanding cycling performance over 100 cycles without significant dimensional changes.

[Full Paper]
Eunjun Park, Min-Sik Park, Jaewoo Lee, Ki Jae Kim, Goojin Jeong, Jung Ho Kim, Young-Jun Kim, Hansu Kim
ChemSusChem 2015, 8, No. 4, 688. Read article.

Simultaneous Genotyping of Multiple Somatic Mutations by Using a Clamping PNA and PNA Detection Probes

Simultaneous Genotyping of Multiple Somatic Mutations by Using a Clamping PNA and PNA Detection Probes

A novel method of simultaneous detection of multiple mutations and a melting curve analysis was developed using clamping PNA/detection PNA probes. Each PNA probe was designed to have a specific melting temperature by the introduction of γ-PNA monomers. This technique was successfully applied to the detection of six genotypes in two different mutations of K-RAS at the same time.

[Communication]
Yong-Tae Kim, Jin Woo Kim, Sung Kee Kim, Goon Ho Joe, In Seok Hong
ChemBioChem 2015, 16, No. 2, 209. Read article.

A Visible-Light Harvesting System for CO2 Reduction Using a RuII–ReI Photocatalyst Adsorbed in Mesoporous Organosilica

A Visible-Light Harvesting System for CO2 Reduction Using a RuII–ReI Photocatalyst Adsorbed in Mesoporous Organosilica

Light my CO2: A photocatalytic system for CO2 reduction exhibiting visible-light harvesting is developed by preparing a hybrid consisting of a RuII-ReI complex as photocatalyst and a periodic mesoporous organosilica as light harvester. The light-harvesting ability of the hybrid enhances the photocatalytic activity for CO evolution by a factor of up to ten.

[Communication]
Yutaro Ueda, Hiroyuki Takeda, Tatsuto Yui, Kazuhide Koike, Yasutomo Goto, Shinji Inagaki, Osamu Ishitani
ChemSusChem 2015, 8, No. 3, 439. Read article.

Through the Maze: Cross-Coupling Pathways to a Helical Hexaphenyl “Geländer” Molecule

Through the Maze: Cross-Coupling Pathways to a Helical Hexaphenyl “Geländer” Molecule

The synthesis of a helical, interlinked Geländer (banister) type hexaphenyl oligomer is symbolized in the figure as a maze; this is a representation of both the often convoluted synthetic possibilities as well as the successful resolution of the maze to reach the target structure.

[Full Paper]
Michel Rickhaus, Linda Maria Bannwart, Oliver Unke, Heiko Gsellinger, Daniel Häussinger, Marcel Mayor
Eur. J. Org. Chem. 2015, No. 4, 786. Read article.

Assessment of the 3 D Pore Structure and Individual Components of Preshaped Catalyst Bodies by X-Ray Imaging

Assessment of the 3 D Pore Structure and Individual Components of Preshaped Catalyst Bodies by X-Ray Imaging

Catalyst bodies in 3 D: The assessment of the 3 D pore structure and components of catalyst bodies in the nanoscale is crucial to understand the fluid catalytic-cracking process (FCC). Modern X-ray imaging techniques allow visualization and quantification of the 3 D pore structure, as well as the material components of FCC catalyst bodies, at this critical scale. These techniques help to improve the manufacture of these catalyst bodies by tuning the pore size and connectivity in a controlled manner.

[Communication]
Julio C. da Silva, Kevin Mader, Mirko Holler, David Haberthür, Ana Diaz, Manuel Guizar-Sicairos, Wu-Cheng Cheng, Yuying Shu, Jörg Raabe, Andreas Menzel, Jeroen A. van Bokhoven
ChemCatChem 2015, 7, No. 3, 413. Read article.

Triphenylacetic Acid Amides: Molecular Propellers with Induced Chirality

Triphenylacetic Acid Amides: Molecular Propellers with Induced Chirality

Weak but cooperative intramolecular interactions, either CH···O hydrogen bonds or local CH/CO dipole/dipole interactions, play a key role in the process of spectacular chirality transfer in triphenylacetamides.

[Full Paper]
Natalia Prusinowska, Wioletta Bendzińska-Berus, Maciej Jelecki, Urszula Rychlewska, Marcin Kwit
Eur. J. Org. Chem. 2015, No. 4, 738. Read article.

Genome Mining-Directed Activation of a Silent Angucycline Biosynthetic Gene Cluster in Streptomyces chattanoogensis

Genome Mining-Directed Activation of a Silent Angucycline Biosynthetic Gene Cluster in Streptomyces chattanoogensis

No longer hidden: Overexpression of a pathway-specific regulator gene under the constitutive ermE* promoter led to activation of a cryptic angucycline biosynthetic gene cluster. Two novel members of the angucycline family of antibiotics were isolated and elucidated.

[Full Paper]
Zhenxing Zhou, Qingqing Xu, Qingting Bu, Yuanyang Guo, Shuiping Liu, Yu Liu, Yiling Du, Yongquan Li
ChemBioChem 2015, 16, No. 3, 496. Read article.

Investigating the Anti-leishmanial Effects of Linear Peptoids

Investigating the Anti-leishmanial Effects of Linear Peptoids

L. mex. meets its match: Peptoids—a class of peptide mimetics—have demonstrated their activities against a range of bacterial infections. In this work, we studied the anti-leishmanial properties of linear peptoids, which were observed to have promising activity against Leishmania mexicana axenic amastigotes, a causative agent of cutaneous leishmaniasis.

[Communication]
Gabriela A. Eggimann, Hannah L. Bolt, Paul W. Denny, Steven L. Cobb
ChemMedChem 2015, 10, No. 2, 233. Read article.

Bifunctional Silver(I) Complex-Catalyzed CO2 Conversion at Ambient Conditions: Synthesis of α-Methylene Cyclic Carbonates and Derivatives

Bifunctional Silver(I) Complex-Catalyzed CO2 Conversion at Ambient Conditions: Synthesis of α-Methylene Cyclic Carbonates and Derivatives

Catalytic fixation of CO2: [(PPh3)2Ag]2CO3 is proven to be a robust bifunctional catalyst for the chemical upgrading of CO2 at atmospheric pressure to produce valuable compounds at ambient conditions. [(PPh3)2Ag]2CO3 can activate both CO2 and propargylic alcohol, and promote the subsequent intramolecular nucleophilic cyclization.

[Full Paper]
Qing-Wen Song, Wei-Qiang Chen, Ran Ma, Ao Yu, Qiu-Yue Li, Yao Chang, Liang-Nian He
ChemSusChem 2015, 8, No. 5, 821. Read article.

Expeditious Synthesis of Enantiopure, Orthogonally Protected Bis-α-Amino Acids (OPBAAs) and their Use in a Study of Nod1 Stimulation

Expeditious Synthesis of Enantiopure, Orthogonally Protected Bis-α-Amino Acids (OPBAAs) and their Use in a Study of Nod1 Stimulation

Give it a nod: A concise preparation of structurally diverse OPBAAs bearing three orthogonally protecting groups and a spacer of varied length has been developed. Using these versatile building blocks, a series of small peptides inspired from peptidoglycan fragments were synthesized and then studied for their ability to activate human Nod1 receptor in the innate immune response through the NF-κB pathway.

[Full Paper]
Po-Ting Chen, Cheng-Kun Lin, Chih-Ju Tsai, Duen-Yi Huang, Fu-Yao Nien, Wan-Wan Lin, Wei-Chieh Cheng
Chem. Asian J. 2015, 10, No. 2, 474. Read article.

Crystal Structures and Redox Responses Coupled with Ion Recognition of p-Benzoquinone- and Hydroquinone-Fused [18]crown-6

Crystal Structures and Redox Responses Coupled with Ion Recognition of p-Benzoquinone- and Hydroquinone-Fused [18]crown-6

Like jewels in a crown: Crystal structures of p-benzoquinone (BQ)- and hydroquinone-fused [18]crown-6 derivatives were investigated. The redox properties of BQ-fused [18]crown-6 derivatives, coupled with ion capturing, were dominated by electrostatic interactions and the solvation energy.

[Full Paper]
Takayuki Kobayashi, Yuta Nakane, Takashi Takeda, Norihisa Hoshino, Hidetoshi Kawai, Tomoyuki Akutagawa
Chem. Asian J. 2015, 10, No. 2, 390. Read article.

Site-Directed and Global Incorporation of Orthogonal and Isostructural Noncanonical Amino Acids into the Ribosomal Lasso Peptide Capistruin

Site-Directed and Global Incorporation of Orthogonal and Isostructural Noncanonical Amino Acids into the Ribosomal Lasso Peptide Capistruin

Expansion of the peptidic code: Supplementation-based incorporation (SPI) and stop-codon suppression (SCS) approaches were used for co-translational incorporation of noncanonical amino acids into the lasso peptide, capistruin. This use of synthetic biology gives a new way to produce lasso peptides in vivo starting from a wide range of amino acids.

[Full Paper]
Rashed S. Al Toma, Anja Kuthning, Matthias P. Exner, Alexander Denisiuk, Juliane Ziegler, Nediljko Budisa, Roderich D. Süssmuth
ChemBioChem 2015, 16, No. 3, 503. Read article.

Preparation and Catalytic Activity of BINOL-Derived Silanediols

Preparation and Catalytic Activity of BINOL-Derived Silanediols

A family of BINOL-derived enantiopure silanediols has been prepared and studied. The effect of the substitution pattern of the BINOL backbone on catalyst performance is detailed. The acidities and chloride binding constants are also reported for this new and exciting class of hydrogen-bond donor (HBD) catalysts.

[Full Paper]
Joshua M. Wieting, Thomas J. Fisher, Andrew G. Schafer, Michael D. Visco, Judith C. Gallucci, Anita E. Mattson
Eur. J. Org. Chem. 2015, No. 3, 525. Read article.

New Catalyst Series from the Sol–Gel-Entrapment of Gold Nanoparticles in Organically Modified Silica Matrices: Proof of Performance in a Model Oxidation Reaction

New Catalyst Series from the Sol–Gel-Entrapment of Gold Nanoparticles in Organically Modified Silica Matrices: Proof of Performance in a Model Oxidation Reaction

Time for gold catalysis to get real: The subtle encapsulation of gold nanoparticles in sol–gel organosilica opens the route to effective heterogeneous oxidation catalysts. The fine-tuneable hydrophilic and hydrophobic regions around the active metal site, the exceptionally high inner mesoporosity, and the enhanced chemical and physical stability of the organosilica matrix indicate forthcoming practical applications of redox catalysis based on gold.

[Full Paper]
Rosaria Ciriminna, Alexandra Fidalgo, Valerica Pandarus, François Béland, Laura M. Ilharco, Mario Pagliaro
ChemCatChem 2015, 7, No. 2, 254. Read article.

Metal Nanoparticles Immobilized on Carbon Nanodots as Highly Active Catalysts for Hydrogen Generation from Hydrazine in Aqueous Solution

Metal Nanoparticles Immobilized on Carbon Nanodots as Highly Active Catalysts for Hydrogen Generation from Hydrazine in Aqueous Solution

Dot dot dot: Highly dispersed bimetallic PtNi nanoparticles with different PtNi compositions have been immobilized on ZIF-8-derived carbon nanodots (CNDs). These materials show high catalytic activity and durability for hydrogen generation from the decomposition of hydrazine in aqueous solution at room temperature.

[Full Paper]
Jian-Ke Sun, Qiang Xu
ChemCatChem 2015, 7, No. 3, 526. Read article.

Promiscuity and the Conformational Rearrangement of Drug-Like Molecules: Insight from the Protein Data Bank

Promiscuity and the Conformational Rearrangement of Drug-Like Molecules: Insight from the Protein Data Bank

Promiscuity in the PDB: A dataset was prepared from 100 drug-like ligands found crystallized in multiple PDB structures that bind to a pair of biological targets with similar in vitro affinity. Compounds were less likely to change conformation upon binding to different proteins if they were highly ligand efficient and had few rotatable bonds. These findings have implications for medicinal chemistry strategies to improve ligand selectivity profiles.

[Communication]
Michael W. He, Patrick S. Lee, Zachary K. Sweeney
ChemMedChem 2015, 10, No. 2, 238. Read article.

Formation of Intermetallic Compounds by Reactive Metal–Support Interaction: A Frequently Encountered Phenomenon in Catalysis

Formation of Intermetallic Compounds by Reactive Metal–Support Interaction: A Frequently Encountered Phenomenon in Catalysis

Strong and stronger: The origin and manifestation of the reactive metal–support interaction (RMSI) as a new type of metal–support interaction are highlighted in selected examples and the structural and catalytic consequences discussed. This new term more accurately describes the most extreme form of metal–support interaction, that is, intermetallic compound formation following high-temperature reduction of oxide-supported metal catalysts.

[Review]
Simon Penner, Marc Armbrüster
ChemCatChem 2015, 7, No. 3, 374. Read article.

Control over Nanostructures and Associated Mesomorphic Properties of Doped Self-Assembled Triarylamine Liquid Crystals

Control over Nanostructures and Associated Mesomorphic Properties of Doped Self-Assembled Triarylamine Liquid Crystals

Changing by packing: Chemically tailored triarylamine derivatives readily self-assemble upon visible light irradiation (see figure) to produce doped liquid crystals with complex mesophase behaviors.

[Full Paper]
Yuya Domoto, Eric Busseron, Mounir Maaloum, Emilie Moulin, Nicolas Giuseppone
Chem. Eur. J. 2015, 21, No. 5, 1938. Read article.

Catalyst-Dependent Selectivity in the Relay Catalytic Branching Cascade

Catalyst-Dependent Selectivity in the Relay Catalytic Branching Cascade

DOS prompt: Catalyst-dependent selectivity in the relay catalytic branching cascade has been reported. The reaction of a common type of substrate (alkynols, A) with variable scaffold-building agents (bis-nucleophiles, B) gave two different types of molecular scaffolds (ABa and ABb) and their formation is essentially dependent on the type of catalyst used.

[Communication]
Avinash H. Bansode, Aslam C. Shaikh, Rahul D. Kavthe, Shridhar Thorat, Rajesh G. Gonnade, Nitin T. Patil
Chem. Eur. J. 2015, 21, No. 6, 2319. Read article.

Using Click Chemistry to Tune the Properties and the Fluorescence Response Mechanism of Structurally Similar Probes for Metal Ions

Using Click Chemistry to Tune the Properties and the Fluorescence Response Mechanism of Structurally Similar Probes for Metal Ions

In these scorpionand molecular probes, the triazole connectivity, the carbon linker, and the fluorescent tail all combine to modulate photophysical behavior and metal responsiveness.

[Full Paper]
Sandra Ast, Stefanie Kuke, Peter J. Rutledge, Matthew H. Todd
Eur. J. Inorg. Chem. 2015, No. 1, 58. Read article.

Small-Molecule Inhibitors That Target Protein–Protein Interactions in the RAD51 Family of Recombinases

Small-Molecule Inhibitors That Target Protein–Protein Interactions in the RAD51 Family of Recombinases

FxxA in the crosshairs: Herein we report two lead series of small molecules chemically elaborated from indole-containing fragments that bind to the surface of a humanised RAD51 orthologue. Our most potent compounds possess single-digit micromolar potency and target the FxxA binding site of the protein–protein interaction with BRCA2.

[Full Paper]
Duncan E. Scott, Anthony G. Coyne, Ashok Venkitaraman, Tom L. Blundell, Chris Abell, Marko Hyvönen
ChemMedChem 2015, 10, No. 2, 296. Read article.

An Efficient Catalytic Approach for the Synthesis of Unsymmetrical Siloxanes

An Efficient Catalytic Approach for the Synthesis of Unsymmetrical Siloxanes

An efficient methodology for the synthesis of unsymmetrical disiloxanes by means of catalytic one-pot hydrolysis/O-silylation of alkoxysilanes with allylsilanes (via silanol intermediates) in the presence of scandium(III) trifluoromethanesulfonate under mild conditions is described. Unsaturated siloxane products are used as substrates for further functionalization through the catalytic hydrosilylation reaction.

[Full Paper]
Grzegorz Hreczycho
Eur. J. Inorg. Chem. 2015, No. 1, 67. Read article.

Platinum Diolefin Complexes – Synthesis, Structures, and Cytotoxicity

Platinum Diolefin Complexes – Synthesis, Structures, and Cytotoxicity

Organometallic diolefin platinum(II) complexes [(∥∥)PtCl2], [(∥∥)Pt(R)(L)] and [(∥∥)Pt(R)2] are synthesised and characterised. Cytotoxicity experiments (HT-29 and MCF-7 cancer cell lines) show that the introduction of labile diolefin ligands ∥∥ or labile coligands does not lead to increased cytotoxicity compared with that of the established 1,5-cyclooctadiene derivatives.

[Full Paper]
Anna Lüning, Michael Neugebauer, Verena Lingen, Alexander Krest, Kathrin Stirnat, Glen B. Deacon, Penny R. Drago, Ingo Ott, Julia Schur, Ingo Pantenburg, Gerd Meyer, Axel Klein
Eur. J. Inorg. Chem. 2015, No. 2, 226. Read article.

The Generation Effect: Cavity Accessibility in Dense-Shell Polyphenylene Dendrimers

The Generation Effect: Cavity Accessibility in Dense-Shell Polyphenylene Dendrimers

It's all relative: The confined geometry of polyphenylene dendrimers leads to a clear generation effect because the size and access to the voids in these dendrimers is determined by their generation. Host–guest behavior to benzene, toluene, and xylenes (BTX) analytes was investigated by using quartz crystal microbalances.

[Communication]
Malte Brutschy, René Stangenberg, Cornelia Beer, Daniel Lubczyk, Martin Baumgarten, Klaus Müllen, Siegfried R. Waldvogel
ChemPlusChem 2015, 80, No. 1, 54. Read article.

High-Density Display of Protein Ligands on Self-Assembled Capsules via Noncovalent Fluorous Interactions

High-Density Display of Protein Ligands on Self-Assembled Capsules via Noncovalent Fluorous Interactions

Getting a lot of coverage: Display of bioactive ligands is an important tool in chemical biology. This communication reports the display of sugar and biotin molecules on sub-100 nm-sized capsules with a high surface coverage using fluorous interactions between fluorous-tagged ligands and a fullerene vesicle covered with fluorous chains. Even after the high-density ligand display and protein binding, the capsule retained its structural integrity, in contrast to lipid vesicles.

[Full Paper]
Koji Harano, Junya Yamada, Shinichiro Mizuno, Eiichi Nakamura
Chem. Asian J. 2015, 10, No. 1, 172. Read article.

Boosting Activation of Oxygen Molecules on C60 Fullerene by Boron Doping

Boosting Activation of Oxygen Molecules on C60 Fullerene by Boron Doping

B enhanced: Density functional calculations suggest that boron-doped fullerene C60 shows excellent performance in catalyzing the activation of oxygen molecules and the relative oxygen reduction reaction (see figure).

[Article]
Qiao-Zhi Li, Jia-Jia Zheng, Jing-Shuang Dang, Xiang Zhao
ChemPhysChem 2015, 16, No. 2, 390. Read article.

A Chemoenzymatic and Fully Stereocontrolled Total Synthesis of the Antibacterial Natural Product (−)-Platencin

A Chemoenzymatic and Fully Stereocontrolled Total Synthesis of the Antibacterial Natural Product (−)-Platencin

Just apply enzymes, metals, and heat: A reaction sequence that involves enzymatic dihydroxylation, auxiliary-controlled alkylation, directed metalation, then Stille cross-coupling protocols provides a tetraene that engages in a thermally induced intramolecular Diels–Alder cycloaddition reaction (see scheme). The resulting adduct can be elaborated to the potent antibacterial agent (−)-platencin.

[Full Paper]
Ee Ling Chang, Brett D. Schwartz, Alistair G. Draffan, Martin G. Banwell, Anthony C. Willis
Chem. Asian J. 2015, 10, No. 2, 427. Read article.

Exploring the Free Energy and Conformational Landscape of tRNA at High Temperature and Pressure

Exploring the Free Energy and Conformational Landscape of tRNA at High Temperature and Pressure

RNA under pressure! Exploration of the conformational and free-energy landscape of the 76-residue yeast phenylalanine transfer RNA (tRNAPhe; see figure) reveals that RNA unfolding differs not only from protein unfolding but also from DNA melting. Compared with the pronounced temperature effect, pressure-dependent changes in the secondary structure of tRNAPhe are small, however, even up to the 1000 MPa range.

[Article]
Caroline Schuabb, Melanie Berghaus, Christopher Rosin, Roland Winter
ChemPhysChem 2015, 16, No. 1, 138. Read article.

Responsive Aqueous Foams

Responsive Aqueous Foams

Responsiveness of aqueous foams: Responsive aqueous foams refer to foams for which the stability can be switched between stable and unstable states with a change in environment or with external stimuli. The different strategies to develop this soft material are reviewed. These responsive foams can find potential applications in diverse industries, in which both stabilization and on-demand destabilization of a foam is required.

[Minireview]
Anne-Laure Fameau, Adrian Carl, Arnaud Saint-Jalmes, Regine von Klitzing
ChemPhysChem 2015, 16, No. 1, 66. Read article.

Electrochemical Conversion of CO2 into Negative Electrode Materials for Li-Ion Batteries

Electrochemical Conversion of CO2 into Negative Electrode Materials for Li-Ion Batteries

Capture the energy: CO2 was captured in molten LiCl–Li2CO3 salt and subsequently converted into amorphous carbon on the cathode and oxygen gas on the inert anode. The obtained carbon displays good performance as a negative electrode material for Li-ion batteries, thus demonstrating the feasibility of this energy conversion and storage process.

[Article]
Jianbang Ge, Liwen Hu, Wei Wang, Handong Jiao, Shuqiang Jiao
ChemElectroChem 2015, 2, No. 2, 224. Read article.

Dye-Sensitized Solar Cell Counter Electrodes Based on Carbon Nanotubes

Dye-Sensitized Solar Cell Counter Electrodes Based on Carbon Nanotubes

Counter strike: Platinum-based counter electrodes and the application of carbon nanotubes (CNTs) and their derivatives as promising alternatives to this precious platinum cathode in dye-sensitized solar cells are reviewed. On the basis of recent advances, promising research directions for the future accomplishment of CNT-based materials in this context are presented.

[Minireview]
Seunghwa Hwang, Munkhbayar Batmunkh, Md J. Nine, Hanshik Chung, Hyomin Jeong
ChemPhysChem 2015, 16, No. 1, 53. Read article.

Voltage-Dependent Capacitance, Aging Effects, and Failure Indicators of Double-Layer Capacitors during Lifetime Testing

Voltage-Dependent Capacitance, Aging Effects, and Failure Indicators of Double-Layer Capacitors during Lifetime Testing

The age test: Aging phenomena, which occur during long-term cycling tests of so-called supercapacitors, complicate the exact determination of capacitance. Voltammetric methods allow useable capacitance, unwanted residual charges, and mechanical failure causes to be distinguished. Polymer-bound carbon electrodes show unexpected failure phenomena at high temperatures and voltages.

[Article]
Peter Kurzweil, Bernhard Frenzel, Andreas Hildebrand
ChemElectroChem 2015, 2, No. 1, 160. Read article.

Mechanistic Details of the Membrane Perforation and Passive Translocation of TAT Peptides

Mechanistic Details of the Membrane Perforation and Passive Translocation of TAT Peptides

The worm turns: How does the TAT peptide translocate across a mammalian cell membrane? Three biophysical methods, which can spatially resolve scales from millimeter (quartz crystal microbalance with dissipation (QCM-D)) and micrometer (scanning electrochemical microscopy (SECM)) to nanometer (AFM), provide evidence for wormhole-like pores (see figure). The SECM image shows that these pores allow redox mediators to pass through to the sensor, but TAT disrupts bacterial-mimetic membranes.

[Full Paper]
Stefania Piantavigna, Muhammad E. Abdelhamid, Chuan Zhao, Xiaohu Qu, George A. McCubbin, Bim Graham, Leone Spiccia, Anthony P. O'Mullane, Lisandra L. Martin
ChemPlusChem 2015, 80, No. 1, 83. Read article.

Slow Exchange of Bidentate Ligands between Rhodium(I) Complexes: Evidence of Both Neutral and Anionic Ligand Exchange

Slow Exchange of Bidentate Ligands between Rhodium(I) Complexes: Evidence of Both Neutral and Anionic Ligand Exchange

Complexes [Rh(acac)(CO)(L1)] and [RhCl(COD)(L2)] undergo a very rapid double exchange of the monodentate phosphine ligands followed by a much slower exchange process involving the bidentate ligands.

[Full Paper]
Si Chen, Eric Manoury, Rinaldo Poli
Eur. J. Inorg. Chem. 2014, No. 34, 5820. Read article.

Receptor-Mediated Uptake of Boron-Rich Neuropeptide Y Analogues for Boron Neutron Capture Therapy

Receptor-Mediated Uptake of Boron-Rich Neuropeptide Y Analogues for Boron Neutron Capture Therapy

NPY for BNCT: Neuropeptide Y (NPY) derivatives selective for only one receptor subtype are internalized into tumor cells that express these specific surface receptors. The cellular uptake of highly boron-loaded NPY analogues and their application as an efficient shuttle system for successful boron neutron capture therapy (BNCT) are demonstrated.

[Full Paper]
Verena M. Ahrens, René Frank, Solveig Boehnke, Christian L. Schütz, Gabriele Hampel, Dorothée S. Iffland, Nicolas H. Bings, Evamarie Hey-Hawkins, Annette G. Beck-Sickinger
ChemMedChem 2015, 10, No. 1, 164. Read article.

Effect of Synthesis Parameters on the Electrochemical Properties of High-Surface-Area Mesoporous Titanium Oxide with Polypyrrole Nanowires in the Pores

Effect of Synthesis Parameters on the Electrochemical Properties of High-Surface-Area Mesoporous Titanium Oxide with Polypyrrole Nanowires in the Pores

Pure pore-fection: High-surface-area mesoporous TiO2 with polypyrrole nanowires within the pores are synthesised and fully characterised. The variation of the polymer-loading level and pore size is explored to optimise electrochemical performance.

[Article]
Luke A. C. Smith, Frederick Romer, Michel L. Trudeau, Mark E. Smith, John V. Hanna, David M. Antonelli
ChemElectroChem 2014, 1, No. 12, 2153. Read article.

NaGdF4 Nanoparticles Coated with Functionalised Ethylenediaminetetraacetic Acid as Versatile Probes for Dual Optical and Magnetic Resonance Imaging

NaGdF4 Nanoparticles Coated with Functionalised Ethylenediaminetetraacetic Acid as Versatile Probes for Dual Optical and Magnetic Resonance Imaging

Caught on camera: NaGdF4 nanoparticles coated with ethylenediaminetetraacetic acid (EDTA) chelators functionalized with organic moieties and luminescent dyes were prepared and characterized, and their potential as dual probes for optical/magnetic resonance imaging (MRI) imaging was investigated (see figure).

[Full Paper]
Fabio Carniato, Lorenzo Tei, Suratchanee Phadngam, Ciro Isidoro, Mauro Botta
ChemPlusChem 2015, 80, No. 3, 503. Read article.

Azacrown Ethers from Mustard Carbonate Analogues

Azacrown Ethers from Mustard Carbonate Analogues

Crowning glory: Several diazacrown ethers incorporating nitrogen mustard moieties have been prepared by treating harmless mustard carbonates with aromatic diols in the absence of any base under pseudo-high dilution conditions (see scheme). This novel synthesis relied upon the anchimeric effect of the nitrogen mustard carbonate.

[Communication]
Fabio Aricò, Ilina Udrea, Marco Crisma, Pietro Tundo
ChemPlusChem 2015, 80, No. 3, 471. Read article.

Non-Invasive Probing of Nanoparticle Electrostatics

Non-Invasive Probing of Nanoparticle Electrostatics

Not what you might think: A new and non-invasive technique to probe the electrostatic interaction between surface-charged nanoparticles and a charged metal/solution interface shows that electrostatic effects are insignificant in all but very dilute electrolytes.

[Article]
Kristina Tschulik, Wei Cheng, Christopher Batchelor-McAuley, Stuart Murphy, Dario Omanović, Richard G. Compton
ChemElectroChem 2015, 2, No. 1, 112. Read article.